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J-GLOBAL ID：200902237128581199   Reference number：08A0524378

Pharmacogenomics of Cardiovascular Pharmacology: Development of an Informatics System for Analysis of DNA Microarray Data With a Focus on Lipid Metabolism

心血管薬理学の薬理ゲノミクス-脂質代謝に焦点を置いたDNAマイクロアレイデータの分析のための情報科学システムの開発

Author (7)： TAKAHARA Yoshiyuki (PharmaFrontier Co., Ltd., JPN) ,  KOBAYASHI Tomoko (PharmaFrontier Co., Ltd., JPN) ,  TAKEMOTO Kazuhisa (PharmaFrontier Co., Ltd., JPN) ,  ADACHI Tetsuya (Dep. of Genomic Drug Discovery Sci., Graduate School of Pharmaceutical Sciences, Kyoto Univ., JPN) ,  OSAKI Ken (World Fusion Co., Ltd., JPN) ,  KAWAHARA Kozo (World Fusion Co., Ltd., JPN) ,  TSUJIMOTO Gozoh (Dep. of Genomic Drug Discovery Sci., Graduate School of Pharmaceutical Sciences, Kyoto Univ., JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 107  Issue： 1  Page： 1-7 (J-STAGE)  Publication year： 2008 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： lipid metabolism ,...
Semi thesaurus term： insulin ,...

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JST classification (3)： Molecular and genetic information processing  (JE15040B) ,  Drugs acting on circulatory system in general  (GW07010C) ,  Drugs acting on metabolism in general  (GW13010F)

Reference (8)：

• KRALLINGER, M. Text-mining approaches in molecular biology and biomedicine. Drug Discovery Today. 2005, 10, 439-445
• SIVACHENKO, AY. Pathway analysis software as a tool for drug target selection, prioritization and validation of drug mechanism. Expert Opin Ther Targets. 2007, 11, 411-421
• SOUKAS, A. Direct transcriptional profiles of adipogenesis in vivo and in vitro. J Biol Chem. 2001, 276, 34167-34174
• MATSUZAWA, Y. Adipocytokines and metabolic syndrome. Semi Vasc Med. 2005, 5, 34-39
• SHARMA, AM. Peroxisome proliferator-activated receptor gamma and adipose tissue-understanding obesity-related changes in regulation of lipid and glucose metabolism. J Clin Endocrinol Metab. 2007, 92, 386-395

Terms in the title (9)： 心 ,  血管薬理学 ,  薬理ゲノミクス ,  脂質代謝 ,  焦点 ,  DNAマイクロアレイ ,  分析 ,  情報科学 ,  開発