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J-GLOBAL ID：200902238828785760   Reference number：07A0802679

Valproate induces apoptosis by inducing accumulation of neutral lipids which was prevented by disruption of the SIR2 gene in Saccharomyces cerevisiae

Saccharomyces cerevisiaeにおいてバルプロ酸は中性脂質の蓄積誘導によりアポトーシスを誘導し,SIR2遺伝子の破壊により阻止される

Author (6)： SUN Qi (Dep. of Biochemistry 2nd, Interdisciplinary Graduate School of Medicine and Engineering, Univ. of Yamanashi, 1110 ...) ,  SUN Qi (Dep. of Immunology, Inner Mongolia Medical Coll., Xin Hua Street, No. 5 Hohhot, Inner Mongolia 010059, CHN) ,  BI Lifu (Dep. of Immunology, Inner Mongolia Medical Coll., Xin Hua Street, No. 5 Hohhot, Inner Mongolia 010059, CHN) ,  SU Xiulan (Dep. of Immunology, Inner Mongolia Medical Coll., Xin Hua Street, No. 5 Hohhot, Inner Mongolia 010059, CHN) ,  TSURUGI Kunio (Dep. of Biochemistry 2nd, Interdisciplinary Graduate School of Medicine and Engineering, Univ. of Yamanashi, 1110 ...) ,  MITSUI Kazuhiro (Dep. of Biochemistry 2nd, Interdisciplinary Graduate School of Medicine and Engineering, Univ. of Yamanashi, 1110 ...)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 581  Issue： 21  Page： 3991-3995  Publication year： Aug. 21, 2007 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 短報  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *Saccharomyces cerevisiae ,...
Semi thesaurus term： HDA1遺伝子 ,...

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JST classification (2)： Microorganism biochemistry  (EG03020N) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Valproic acid

Terms in the title (10)： Saccharomyces ,  バルプロ酸 ,  中性脂質 ,  蓄積 ,  誘導 ,  アポトーシス ,  Sir2 ,  遺伝子 ,  破壊 ,  阻止