Art

J-GLOBAL ID：200902238853856035   Reference number：05A0319980

Inhibitory effects of asiatic acid and CPT-11 on growth of HT-29 cells

HT-29細胞の成長に及ぼすアシアチン酸とCPT-11の阻害効果

Author (7)： BUNPO Piyawan (Univ. Tokushima Graduate School, Tokushima, JPN) ,  KATAOKA Keiko (Univ. Tokushima Graduate School, Tokushima, JPN) ,  ARIMOCHI Hideki (Univ. Tokushima Graduate School, Tokushima, JPN) ,  NAKAYAMA Haruyuki (Univ. Tokushima Graduate School, Tokushima, JPN) ,  KUWAHARA Tomomi (Univ. Tokushima Graduate School, Tokushima, JPN) ,  VINITKETKUMNUEN Usanee (Chiang Mai Univ., Chiang Mai, THA) ,  OHNISHI Yoshinari (Univ. Tokushima Graduate School, Tokushima, JPN)
Material： Journal of Medical Investigation  (JMI)
Volume： 52  Issue： 1-2  Page： 65-73  Publication year： Feb. 2005 
JST Material Number： G0657A  ISSN： 1343-1420  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *pentacyclic triterpene ,...
Semi thesaurus term： アシアチン酸 ,...

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JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Plant biochemistry  (EH01050J)

Substance index (2)： CPT-11 ,  Asiatic acid

Reference (51)：

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• 2. Bunpo P, Kataoka K, Arimochi H, Nakayama H, Kuwahara T, Bando Y, Izumi K, Vinitketkumnuen U, Ohnishi Y: Inhibitory effects of Centella asiatica on azoxymethane-induced aberrant crypt focus formation and carcinogenesis in the intestines of F344 rats. Food Chem Toxicol, 42: 1987-1997, 2004
• 3. Cha HJ, Park MT, Chung HY, Kim ND, Sato H, Seiki M, Kim KW: Ursolic acid-induced down-regulation of MMP-9 gene is mediated through the nuclear translocation of glucocorticoid receptor in HT1080 human fibrosarcoma cells. Oncogene 16: 771-778, 1998
• 4. Sohn KH, Lee HY, Chung HY, Young HS, Yi SY, Kim KW: Anti-angiogenic activity of triterpene acids. Cancer Lett 94: 213-218, 1995
• 5. Novotny L, Vachalkova A, Biggs D: Ursolic acid: an anti-tumorigenic and chemopreventive activity. Minireview. Neoplasma 48: 241-246, 2001

Terms in the title (5)： 細胞 ,  成長 ,  アシアチン酸 ,  CPT-11 ,  阻害効果