Art

J-GLOBAL ID：200902239498457775   Reference number：05A0341985

Sphingosine 1-phosphate acts as a signal molecule in ceramide signal transduction of TNF-α-induced activator protein-1 in osteoblastic cell line MC3T3-E1 cell

スフィンゴシン1りん酸は骨芽細胞様細胞株MC3T3-E1細胞においてTNFアルファ誘発アクチベーター蛋白質1のセラミドシグナル伝達におけるシグナル分子として作用する

Author (9)： TAKESHITA Akira (Meikai Univ. School of Dentistry, Saitama, JPN) ,  SHINODA Hiroyuki (Meikai Univ. School of Dentistry, Saitama, JPN) ,  NAKABAYASHI yasuo (Meikai Univ. School of Dentistry, Saitama, JPN) ,  TAKANO Akiko (Meikai Univ. School of Dentistry, Saitama, JPN) ,  MATSUMOTO Ken (Nissui Pharmaceutical Co., Ltd., Ibarak, JPN) ,  SUETSUGU Mayumi (Meikai Univ. School of Dentistry, Saitama, JPN) ,  MIYAZAWA Kei (Meikai Univ. School of Dentistry, Saitama, JPN) ,  TANAKA Sonoji (Meikai Univ. School of Dentistry, Saitama, JPN) ,  ENDO Hiromasa (Meikai Univ. School of Dentistry, Saitama, JPN)
Material： Journal of Oral Science  (J Oral Sci)
Volume： 47  Issue： 1  Page： 43-51  Publication year： Mar. 2005 
JST Material Number： Z0759A  ISSN： 1343-4934  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Mus musculus ,...
Semi thesaurus term： *cellular signal transduction ,...

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JST classification (4)： Animal metabolism and nutrition in general  (EJ02031R) ,  Gene expression  (EC02040Q) ,  Basic dentistry(= odontology)  (GT01020O) ,  Cell physiology in general  (EF02010S)

Substance index (9)： Sphingosine-1-phosphate ,  N-Acetylsphingosine ,  N-Hexanoylsphingosine ,  N-Octanoylsphingosine ,  DL-threo-Dihydrosphingosine ,  (γ-32P)ATP ,  dCTP ,  DL-threo-PPPP ,  (+-)-PDMP

Reference (51)：

• 1. Mercado FB, Marshall RI, Bartold PM (2003) Inter-relationships between rheumatoid arthritis and periodontal disease. A review. J Clin Periodontol 30, 761-772
• 2. Krane, SM, Goldring MB, Goldring SR (1988) Cytokines. In Cell and molecular biology of vertebrate hard tissues. (Ciba Found Symp. 136), Evered D, Harnett S eds, John Wiley & Sons, Chichester, 239-256
• 3. Buchan G, Barrett K, Turner M, Chantry D, Maini RN, Feldmann M (1988) Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 α. Clin Exp Immunol 73, 449-455
• 4. Romas E, Gillespie MT, Martin TJ (2002) Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis. Bone 30, 340-346
• 5. Graves DT, Cochran D (2003) The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction. J Periodontol 74, 391-401

Terms in the title (11)： スフィンゴシン1りん酸 ,  骨芽細胞様細胞 ,  株 ,  MC3T3-E1細胞 ,  TNFアルファ ,  誘発 ,  アクチベーター ,  蛋白質 ,  セラミド ,  シグナル伝達 ,  シグナル分子