Art

J-GLOBAL ID：200902239527240675   Reference number：08A1164469

Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death

膜蛋白質の誤った翻訳および2成分制御系活性化は抗生物質介在性細胞死を誘発する

Author (9)： KOHANSKI Michael A. (Dep. of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston Univ., 44 ...) ,  KOHANSKI Michael A. (Boston Univ. School of Medicine, 715 Albany Street, Boston, MA 02118, USA) ,  DWYER Daniel J. (Dep. of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston Univ., 44 ...) ,  DWYER Daniel J. (Dep. of Math and Statistics, 111 Cummington Street, Boston Univ., Boston, MA 02215, USA) ,  WIERZBOWSKI Jamey (Dep. of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston Univ., 44 ...) ,  COTTAREL Guillaume (Dep. of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston Univ., 44 ...) ,  COLLINS James J. (Howard Hughes Medical Inst., Boston Univ., 44 Cummington Street, Boston, MA 02215, USA) ,  COLLINS James J. (Dep. of Biomedical Engineering, Center for BioDynamics, and Center for Advanced Biotechnology, Boston Univ., 44 ...) ,  COLLINS James J. (Boston Univ. School of Medicine, 715 Albany Street, Boston, MA 02118, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 135  Issue： 4  Page： 679-690  Publication year： Nov. 14, 2008 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： Membrane Proteins ,  translation (genetics) ,  *oxidative stress ,  *aminoglycoside antibiotics ,  *Cell Death ,  gene expression ,  Escherichia coli ,  bactericidal action ,  citric acid cycle ,  Hydroxyl Radical ,  gene disruption ,  depolarization (physiology) ,  lethality ,  oxidation-reduction reaction ,  cell culture ,  polymerase chain reaction ,  quantitative polymerase chain reaction ,  alicyclic compound ,  oxygen heterocyclic compound ,  aminoalcohol ,  diamine ,  diol ,  secondary amine ,  secondary alcohol ,  amino sugar ,  alditol ,  deoxysugar ,  pyranoside ,  glucoside ,  trisaccharide ,  nitrogen heterocyclic compound ,  aromatic fluorine compound ,  polynuclear aromatic compound ,  keto acid ,  amino acid ,  aromatic compound ,  lactam ,  sulfur heterocyclic compound ,  primary amine ,  Protein Folding ,  *antibacterial drug ,  *antimicrobial drug ,  *drug ,  molecular genetic phenomenon ,  microorganism ,  ketone
Semi thesaurus term： gentamicin ,  qPCR法

JST classification (3)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C) ,  Microorganism physiology in general  (EG03051L) ,  Gene expression  (EC02040Q)

Substance index (4)： Spectinomycin ,  Kanamycin ,  Norfloxacin ,  Ampicillin

Terms in the title (8)： 膜蛋白質 ,  翻訳 ,  2成分 ,  制御系 ,  活性化 ,  抗生物質 ,  細胞死 ,  誘発