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J-GLOBAL ID：200902239805192547   Reference number：03A0586921

Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice

肝細胞傷害の反復はC型肝炎ウイルストランスジェニックマウスにおける肝腫りゅう形成を促進する

Author (9)： KATO T (Tokyo Metropolitan Inst. for Neurosci., Tokyo) ,  MIYAMOTO M (Tokyo Metropolitan Inst. for Neurosci., Tokyo) ,  TAYA C (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  YONEKAWA H (Tokyo Metropolitan Inst. of Medical Sci., Tokyo) ,  OHUE C (Advanced Life Sci. Inst., Inc., Saitama) ,  YAGI S (Advanced Life Sci. Inst., Inc., Saitama) ,  SEKI E (Hyogo Coll. of Medicine, Hyogo) ,  HIRANO T (Hyogo Coll. of Medicine, Hyogo) ,  SHIRAI T (Nagoya City Univ. Postgraduate School of Medical Sci., Nagoya)
Material： Cancer Science  (Cancer Sci)
Volume： 94  Issue： 8  Page： 679-685  Publication year： Aug. 31, 2003 
JST Material Number： F0633A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *hepatic toxicity ,...
Semi thesaurus term： tumorigenesis

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JST classification (1)： Carcinogenic mechanisms and factors  (GE02020C)

Substance index (1)： Carbon Tetrachloride

Reference (40)：

• KIYOSAWA, K. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma : analysis by detection of antibody to hepatitis C virus. Hepatology. 1990, 12, 671-675
• TONG, MJ. Clinical outcomes after transfusion-associated hepatitis C. N Engl J Med. 1995, 332, 1463-1466
• UEMURA, N. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med. 2001, 345, 784-789
• SHARAN, R. Cancer in inflammatory bowel disease. An evidence-based analysis and guide for physicians and patients. Gastroenterol Clin North Am. 2002, 31, 237-254
• BURROUGHS, AK. Primary liver cell cancer in autoimmune chronic liver disease. Br Med J (Clin Res Ed). 1981, 282, 273

Terms in the title (7)： 肝細胞 ,  傷害 ,  反復 ,  C型肝炎ウイルス ,  トランスジェニックマウス ,  肝腫りゅう ,  促進