Art

J-GLOBAL ID：200902240043232358   Reference number：07A0578831

Endothelial Lipase Gene Polymorphism is Associated With Acute Myocardial Infarction, Independently of High-Density Lipoprotein-Cholesterol Levels

内皮性リパーゼ遺伝子多型は,急性心筋梗塞と関連し,高密度リポ蛋白質-コレステロールレベルと無関係である。

Author (12)： SHIMIZU Masakatsu (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  KANAZAWA Kenji (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  HIRATA Ken-ichi (Div. of Cardiovascular and Respiratory Medicine, Dep. of Internal Medicine, Kobe Univ. Graduate School of Medicine) ,  ISHIDA Tatsuro (Div. of Cardiovascular and Respiratory Medicine, Dep. of Internal Medicine, Kobe Univ. Graduate School of Medicine) ,  HIRAOKA Eiji (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  MATSUDA Yasuaki (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  IWAI Chikao (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  MIYAMOTO Yoshitomo (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  HASHIMOTO Masayoshi (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  KAJIYA Teishi (Dep. of Cardiology, Himeji Cardiovascular Center) ,  AKITA Hozuka (Div. of General Medical Sci., Dep. of General Therapeutics, Kobe Univ. Graduate School of Medicine) ,  YOKOYAMA Mitsuhiro (Div. of Cardiovascular and Respiratory Medicine, Dep. of Internal Medicine, Kobe Univ. Graduate School of Medicine)
Material： Circulation Journal  (Circ J)
Volume： 71  Issue： 6  Page： 842-846 (J-STAGE)  Publication year： 2007 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： sterol ,...
Semi thesaurus term： variation(biology)

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JST classification (1)： Cardiovascular system diagnosis  (GJ02000V)

Substance index (1)： Cholesterol

Reference (32)：

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• 2. Hirata K, Dichek HL, Cioffi JA, Choi SY, Leeper NJ, Quintana L, et al. Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem 1999; 274: 14170-14175.
• 3. Jaye M, Lynch KJ, Krawiec J, Marchadier D, Maugeais C, Doan K, et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 1999; 21: 424-428.
• 4. McCoy MG, Sun GS, Marchadier D, Maugeais C, Glick JM, Rader DJ. Characterization of the lipolytic activity of endothelial lipase. J Lipid Res 2002; 43: 921-929.
• 5. Ishida T, Choi S, Kundu RK, Hirata K, Rubin EM, Cooper AD, et al. Endothelial lipase is a major determinant of HDL level. J Clin Invest 2003; 111: 347-355.

Terms in the title (6)： 内皮 ,  リパーゼ ,  遺伝子多型 ,  急性心筋梗塞 ,  高密度リポ蛋白質 ,  コレステロール