Art

J-GLOBAL ID：200902240116837571   Reference number：07A0294554

Up-regulation of ras-GAP genes is reversed by a MEK inhibitor and doxorubicin in v-Ki-ras-transformed NIH/3T3 fibroblasts

ras-GAP遺伝子のアップレギュレーションはv-Ki-ras形質転換NIH/3T3線維芽細胞においてMEK阻害剤とドキソルビシンにより抑制される

Author (10)： HASHII Minako (Dep. of Biophysical Genetics, Kanazawa Univ. Graduate School of Medicine, Kanazawa, JPN) ,  FUKUDA Mitsunori (Lab. of Membrane Trafficking Mechanisms, Dep. of Developmental Biology and Neurosciences, Graduate School of Life ...) ,  NOMURA Hideki (Div. of General Internal Medicine, Kanazawa Univ. Hospital, Kanazawa, JPN) ,  ITO Naoko (Dep. of Biophysical Genetics, Kanazawa Univ. Graduate School of Medicine, Kanazawa, JPN) ,  TAKAHASHI Hiroto (Dep. of Biophysical Genetics, Kanazawa Univ. Graduate School of Medicine, Kanazawa, JPN) ,  HATTORI Seisuke (Div. of Cellular Genome Proteomics, Inst. of Medical Sci., Univ. of Tokyo, Tokyo, JPN) ,  MIKOSHIBA Katsuhiko (Div. of Molecular Neurobiology, Inst. of Medical Sci., Univ. of Tokyo, Tokyo, JPN) ,  MIKOSHIBA Katsuhiko (Lab. for Developmental Neurobiology, Brain Sci. Inst., RIKEN, Wako, JPN) ,  NODA Makoto (Dep. of Molecular Oncology, Kyoto Univ. Graduate School of Medicine, Kyoto, JPN) ,  HIGUCHI Yoshihiro (Dep. of Molecular Pharmacology, Kanazawa Univ. Graduate School of Medicine, Kanazawa, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 356  Issue： 2  Page： 374-380  Publication year： May. 04, 2007 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Ras protein ,...
Semi thesaurus term： *Ras ,...

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JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Substance index (2)： Doxorubicin ,  Trichostatin A

Terms in the title (10)： Ras ,  GAP ,  遺伝子 ,  アップレギュレーション ,  KI ,  形質転換 ,  NIH ,  線維芽細胞 ,  MEK阻害剤 ,  ドキソルビシン