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J-GLOBAL ID：200902240864483367   Reference number：05A0684842

Development and Application of a New ADAMTS13 Assay for TTP Diagnosis

薬剤起因性血小板減少症の病態と検査(ITP,HIT,TTP)(4)TTP迅速診断を目的とした新規ADAMTS13測定法の開発と応用

Author (2)： KOKAME KOICHI (国立循環器病セ 研) ,  MIYATA TOSHIYUKI (国立循環器病セ 研)
Material： 臨床病理  (日本臨床検査医学会誌)
Volume： 53  Issue： 7  Page： 639-645  Publication year： Jul. 25, 2005 
JST Material Number： Z0687A  ISSN： 0047-1860  CODEN： RBYOAI  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human ,...
Semi thesaurus term： TTP ,...

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JST classification (3)： Hematologic diagnosis  (GK02000Y) ,  Enzyme physiology  (EJ02020P) ,  Medical examinations in general  (GC02010L)

Reference (20)：

• MOAKE, JL. Unusually large plasma factor VIII : von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. N Engl J Med. 1982, 307, 1432-1435
• SOEJIMA, K. A novel human metalloprotease synthesized in the liver and secreted into the blood : possibly, the von Willebrand factor-cleaving protease?. J Biochem. 2001, 130, 475-480
• ZHENG, X. Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. J Biol Chem. 2001, 276, 41059-41063
• LEVY, GG. Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature. 2001, 413, 488-494
• BANNO, F. Identification of strain-specific variants of mouse Adamts13 gene encoding von Willebrand factor-cleaving protease. J Biol Chem. 2004, 279, 30896-30903

Terms in the title (12)： 薬剤 ,  起因 ,  血小板減少症 ,  病態 ,  検査 ,  ITP ,  TTP ,  迅速診断 ,  ADAMTS13 ,  測定法 ,  開発 ,  応用