Art

J-GLOBAL ID：200902241768734908   Reference number：09A0132415

Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis

好熱性真核生物Alvinella pompejana由来のスーパーオキシドジスムターゼ:構造,安定性,機構,及び筋萎縮性側索硬化症への洞察

Author (11)： SHIN David S. (Dep. of Molecular Biology, The Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., La Jolla, CA 92037, USA) ,  DIDONATO Michael (Dep. of Molecular Biology, The Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., La Jolla, CA 92037, USA) ,  BARONDEAU David P. (Dep. of Molecular Biology, The Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., La Jolla, CA 92037, USA) ,  HURA Greg L. (Advanced Light Source, Lawrence Berkeley National Lab., Berkeley, CA 94720, USA) ,  HITOMI Chiharu (Dep. of Molecular Biology, The Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., La Jolla, CA 92037, USA) ,  BERGLUND J. Andrew (Inst. of Molecular Biology, Univ. of Oregon, Eugene, OR 97403, USA) ,  GETZOFF Elizabeth D. (Dep. of Molecular Biology, The Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., La Jolla, CA 92037, USA) ,  CARY S. Craig (Coll. of Marine Studies, Univ. of Delaware, Lewes, DE 19958, USA) ,  CARY S. Craig (Dep. of Biological Sciences, Univ. of Waikato, Hamilton 3240, NZL) ,  TAINER John A. (Dep. of Molecular Biology, The Skaggs Inst. for Chemical Biology, The Scripps Res. Inst., La Jolla, CA 92037, USA) ,  TAINER John A. (Advanced Light Source, Lawrence Berkeley National Lab., Berkeley, CA 94720, USA)
Material： Journal of Molecular Biology  (J Mol Biol)
Volume： 385  Issue： 5  Page： 1534-1555  Publication year： Feb. 06, 2009 
JST Material Number： D0124B  ISSN： 0022-2836  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Polychaeta ,  marine animal ,  *amyotrophic lateral sclerosis ,  eucaryote ,  *superoxide dismutase ,  thermal stability ,  gene cloning ,  small angle X-ray scattering ,  crystal structure ,  dimer ,  active site ,  intermolecular interaction ,  enzyme reaction mechanism ,  metal ion ,  electron transfer ,  amyloid ,  thermophilic ,  amino acid sequence ,  folded structure ,  loop structure
Semi thesaurus term： Alvinella pompejana ,  *Cu/Zn superoxide dismutase ,  Catalysis ,  amyloid fibril

JST classification (2)： Enzyme in general  (EB09010D) ,  Nervous system diseases  (GN03000O)

Terms in the title (6)： 好熱性 ,  真核生物 ,  スーパーオキシドジスムターゼ ,  安定性 ,  筋萎縮性側索硬化症 ,  洞察