Art

J-GLOBAL ID：200902242356106127   Reference number：09A0530776

Further Investigation Into the Mechanism of Tachykinin NK₂ Receptor-Triggered Serotonin Release From Guinea-Pig Proximal Colon

モルモット近位結腸からのタキキニンNK₂受容体誘因セロトニン遊離のメカニズムの更なる検討

Author (3)： KOJIMA Shu-ichi (Dep. of Pharmacology, Dokkyo Medical Univ. School of Medicine, JPN) ,  IKEDA Masashi (Inst. of International Education and Res., Dokkyo Medical Univ. School of Medicine, JPN) ,  KAMIKAWA Yuichiro (Dep. of Pharmacology, Dokkyo Medical Univ. School of Medicine, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 110  Issue： 1  Page： 122-126 (J-STAGE)  Publication year： 2009 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *neurokinin receptor ,...
Semi thesaurus term： C型ボツリヌス毒素 ,...

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JST classification (3)： Receptors on cell membrane  (EF04030C) ,  Biosubstance in general  (EB02010G) ,  Bioactive peptides  (EB08100U)

Substance index (7)： Serotonin ,  Clorgiline ,  Genistein ,  Dithiothreitol ,  Nicardipine ,  Neurokinin A ,  Phenylarsine oxide

Reference (14)：

• GERSHON, MD. The serotonin signaling system : from basic understanding to drug development for functional GI disorders. Gastroenterology. 2007, 132, 397-414
• RACKE, K. Regulation of serotonin release from the intestinal mucosa. Pharmacol Res. 1991, 23, 13-25
• KOJIMA, S. Calcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic mucosa via myenteric neurons and tachykinin NK_2/NK_3 receptors. Br J Pharmacol. 2004, 141, 385-390
• KOJIMA, S. Loperamide inhibits tachykinin NK_3-receptor-triggered serotonin release without affecting NK_2-receptor-triggered serotonin release from guinea-pig colonic mucosa. J Pharmacol Sci. 2005, 98, 175-180
• KOJIMA, S. Calcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic enterochromaffin cells. J Pharmacol Sci. 2003, 91, 173

Terms in the title (6)： モルモット ,  結腸 ,  タキキニン ,  NK2受容体 ,  セロトニン ,  メカニズム