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J-GLOBAL ID：200902246070176735   Reference number：03A0553027

Accumulation of deleted mitochondrial DNA in aging Drosophila melanogaster.

加齢Drosophila melanogasterにおける欠失ミトコンドリアDNAの蓄積

Author (3)： YUI R (Ochanomizu Univ., Tokyo, JPN) ,  OHNO Y (Ochanomizu Univ., Tokyo, JPN) ,  MATSUURA E T (Ochanomizu Univ., Tokyo, JPN)
Material： Genes & Genetic Systems  (Genes & Genet Syst)
Volume： 78  Issue： 3  Page： 245-251  Publication year： Jun. 2003 
JST Material Number： F0386A  ISSN： 1341-7568  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *mitochondrial gene ,...
Semi thesaurus term： Drosophila ,...

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JST classification (1)： Genetic variation  (EC01030Y)

Reference (27)：

• Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., Beal, M. F., and Wallace, D. C. (1992) Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nature Genet. 2, 324-329.
• Cortopassi, G. A., and Arnheim, N. (1990) Detection of a specific mitochondrial DNA deletion in tissues of older humans. Nucleic Acids Res. 18, 6927-6933.
• Cortopassi, G. A., Shibata, D., Soong, N. W., and Arnheim, N. (1992) A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues. Proc. Natl. Acad. Sci. USA 89, 7370-7374.
• Edris, W., Burgett, B., Stine, O. C., and Filburn, C. R. (1994) Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA. Mutat. Res. 316, 69-78.
• Filser, N., Margue, C., and Richter, C. (1997) Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs. Biochem. Biophys. Res. Commun. 233, 102-107.

Terms in the title (5)： 加齢 ,  Drosophila ,  欠失 ,  ミトコンドリアDNA ,  蓄積