Art

J-GLOBAL ID：200902247228685582   Reference number：03A0800676

N-Glycosylation of 2,3-dideoxyfuranose derivatives having a (diethoxyphosphorothioyl)difluoromethyl group at the 3α-position

3α位に(ジエトキシホスホロチオイル)ジフルオロメチル基を持った2,3-ジデオキシフラノース誘導体のN-グリコシル化

Author (5)： MURANO T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  YUASA Y (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  MUROYAMA S (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  YOKOMATSU T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  SHIBUYA S (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 59  Issue： 46  Page： 9059-9073  Publication year： Nov. 10, 2003 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *nucleotide analog ,...
Semi thesaurus term： neighbouring group effect

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JST classification (1)： Nucleosides,nucleotides  (CF10060K)

Substance index (20)： m-Chloroperbenzoic acid ,  (2R)-2,3-Isopropylidenedioxypropanal ,  1-O-Ethyl-3-[difluoro(diethoxyphosphinothioyl)methyl]-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-D-erythro-pentofuranose ,  3-[Difluoro(diethoxyphosphinothioyl)methyl]-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-D-erythro-pentofuranose 1-acetate ,  [[(2S,3S)-2-(Benzyloxymethyl)-5-ethoxytetrahydrofuran-3-yl]difluoromethyl]thiophosphonic acid diethyl ester ,  [[(2S,3S,5S)-2-(Benzoyloxymethyl)-5-ethoxytetrahydrofuran-3-yl]difluoromethyl]thiophosphonic acid diethyl ester ,  [[(2S,3S,5R)-2-(Benzoyloxymethyl)-5-ethoxytetrahydrofuran-3-yl]difluoromethyl]thiophosphonic acid diethyl ester ,  Bis(O-trimethylsilyl)thymine ,  1-[(2R,4S,5S)-4-[(Diethoxythiophophinyl)difluoromethyl]-5-(benzoyloxymethyl)tetrahydrofuran-2-yl]thymine ,  3-[(2R,4S,5S)-4-[(Diethoxythiophophinyl)difluoromethyl]-5-(benzoyloxymethyl)tetrahydrofuran-2-yl]thymine ,  3′-[Difluoro(diethoxyphosphinothioyl)methyl]-5′-O-(tert-butyldiphenylsilyl)-3′-deoxythymidine ,  3′-[Difluoro(diethoxyphosphinothioyl)methyl]-5′-O-(tert-butyldiphenylsilyl)-2′,3′-dideoxyuridine ,  3′-[Difluoro(diethoxyphosphinothioyl)methyl]-5-fluoro-5′-O-(tert-butyldiphenylsilyl)-2′,3′-dideoxyuridine ,  N-Benzoyl-1-[(2R,4S,5S)-4-[(diethoxythiophophinyl)difluoromethyl]-5-(tert-butyldiphenylsilyloxymethyl)tetrahydrofuran-2-yl]cytosine ,  3′-[Difluoro(diethoxyphosphinyl)methyl]-5′-O-(tert-butyldiphenylsilyl)-3′-deoxythymidine ,  3-[(2S,4S,5S)-4-[(Diethoxyphosphinyl)difluoromethyl]-5-(tert-butyldiphenylsilyloxymethyl)tetrahydrofuran-2-yl]thymine ,  6-(Benzoylamino)-9-[(2R,4S,5S)-4-[(diethoxythiophophinyl)difluoromethyl]-5-(tert-butyldiphenylsilyloxymethyl)tetrahydrofuran-2-yl]-9H-purine ,  6-(Benzoylamino)-9-[(2S,4S,5S)-4-[(diethoxythiophophinyl)difluoromethyl]-5-(tert-butyldiphenylsilyloxymethyl)tetrahydrofuran-2-yl]-9H-purine ,  6-(Benzoylamino)-9-[(2R,4S,5S)-4-[(diethoxythiophophinyl)difluoromethyl]-5-(benzyloxymethyl)tetrahydrofuran-2-yl]-9H-purine ,  6-(Benzoylamino)-9-[(2S,4S,5S)-4-[(diethoxythiophophinyl)difluoromethyl]-5-(benzyloxymethyl)tetrahydrofuran-2-yl]-9H-purine

Terms in the title (2)： 誘導体 ,  N-グリコシル化