Art

J-GLOBAL ID：200902249097624933   Reference number：09A0181911

Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81

乳酸は脂肪細胞でオーファンG蛋白質共役受容体,GPR81の活性化を通じて脂肪分解を阻害する

Author (13)： LIU Changlu (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  WU Jiejun (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  ZHU Jessica (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  KUEI Chester (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  YU Jingxue (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  SHELTON Jonathan (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  SUTTON Steven W. (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  LI Xiaorong (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  YUN Su Jin (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  MIRZADEGAN Taraneh (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  MAZUR Curt (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  KAMME Fredrik (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California) ,  LOVENBERG Timothy W. (Johnson & Johnson Pharmaceutical Res. & Dev., LLC, California)
Material： Journal of Biological Chemistry  (J Biol Chem)
Volume： 284  Issue： 5  Page： 2811-2822  Publication year： Jan. 30, 2009 
JST Material Number： E0038A  ISSN： 0021-9258  CODEN： JBCHA3  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： fat cell ,  Rattus ,  Mus musculus ,  human ,  *Lipolysis ,  fatigue (physiology) ,  *membrane receptor ,  hyperlipidemia ,  cultured cell ,  aliphatic alcohol ,  aliphatic carboxylic acid ,  secondary alcohol ,  hydroxy acid ,  3T3 L1 Cells ,  *G protein-coupled receptor ,  Myomorpha ,  metabolic disease
Semi thesaurus term： *GPR81 ,  *G-protein coupled receptor ,  lipemia

JST classification (2)： Metabolism and nutrition of lipids  (EJ02034Q) ,  Receptors on cell membrane  (EF04030C)

Substance index (1)： Lactic acid

Terms in the title (6)： 乳酸 ,  脂肪細胞 ,  G蛋白質共役受容体 ,  活性化 ,  脂肪分解 ,  阻害