Art

J-GLOBAL ID：200902250608995046   Reference number：06A0246818

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

表皮バリアタンパク質フィラグリンの一般的な機能喪失性変異はアトピー性皮膚炎の主要な素因である

Author (28)： PALMER Colin N A (Univ. Dundee, Dundee, GBR) ,  IRVINE Alan D (Our Lady’s Hospital for Sick Children, Dublin, IRL) ,  TERRON-KWIATKOWSKI Ana (Univ. Dundee, Dundee, GBR) ,  ZHAO Yiwei (Univ. Dundee, Dundee, GBR) ,  LIAO Haihui (Univ. Dundee, Dundee, GBR) ,  LEE Simon P (Univ. Dundee, Dundee, GBR) ,  GOUDIE David R (Tayside Univ. Hospitals NHS Trust, Dundee, GBR) ,  SANDILANDS Aileen (Univ. Dundee, Dundee, GBR) ,  CAMPBELL Linda E (Univ. Dundee, Dundee, GBR) ,  SMITH Frances J D (Univ. Dundee, Dundee, GBR) ,  O'REGAN Grainne M (Our Lady’s Hospital for Sick Children, Dublin, IRL) ,  WATSON Rosemarie M (Our Lady’s Hospital for Sick Children, Dublin, IRL) ,  CECIL Jo E (Univ. St. Andrews, Fife, GBR) ,  BALE Sherri J (GeneDx, Maryland, USA) ,  COMPTON John G (GeneDx, Maryland, USA) ,  DIGIOVANNA John J (Brown Medical School, Rhode Island, USA) ,  DIGIOVANNA John J (National Inst. of Health, Maryland, USA) ,  FLECKMAN Philip (Univ. Washington, Washington, USA) ,  LEWIS-JONES Sue (Tayside Univ. Hospitals NHS Trust, Dundee, GBR) ,  ARSECULERATNE Gehan (Tayside Univ. Hospitals NHS Trust, Dundee, GBR) ,  SERGEANT Ann (South Glasgow Univ. Hospitals NHS Trust, Glasgow, GBR) ,  MUNRO Colin S (South Glasgow Univ. Hospitals NHS Trust, Glasgow, GBR) ,  HOUATE Brahim El (Inst. Pasteur, Paris, FRA) ,  MCELREAVEY Ken (Inst. Pasteur, Paris, FRA) ,  HALKJAER Liselotte B (Univ. Hospital, Copenhagen, DNK) ,  BISGAARD Hans (Univ. Hospital, Copenhagen, DNK) ,  MUKHOPADHYAY Somnath (Univ. Hospital, Copenhagen, DNK) ,  MCLEAN W H Irwin (Univ. Dundee, Dundee, GBR)
Material： Nature Genetics  (Nat Genet)
Volume： 38  Issue： 4  Page： 441-446  Publication year： Apr. 10, 2006 
JST Material Number： W0430A  ISSN： 1061-4036  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： Epidermis ,...
Semi thesaurus term： FLG遺伝子

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JST classification (1)： Genetic variation  (EC01030Y)

Terms in the title (6)： 表皮 ,  バリア ,  タンパク質 ,  フィラグリン ,  変異 ,  アトピー性皮膚炎