Art

J-GLOBAL ID：200902250802546180   Reference number：03A0644886

Structure of the Transition State Analog of Medium-Chain Acyl-CoA Dehydrogenase. Crystallographic and Molecular Orbital Studies on the Charge-Transfer Complex of Medium-Chain Acyl-CoA Dehydrogenase with 3-Thiaoctanoyl-CoA

中鎖アシルCoAデヒドロゲナーゼの遷移状態類縁体の構造 3-チアオクタノイルCoAと中鎖アシルCoAデヒドロゲナーゼの電荷移動錯体における結晶学及び分子軌道研究

Author (9)： SATOH A (Osaka City Univ., Osaka) ,  NAKAJIMA Y (Osaka City Univ., Osaka) ,  MIYAHARA I (Osaka City Univ., Osaka) ,  HIROTSU K (Osaka City Univ., Osaka) ,  TANAKA T (Kobe Univ., Kobe) ,  NISHINA Y (Kumamoto Univ., Kumamoto) ,  SHIGA K (Kumamoto Univ., Kumamoto) ,  TAMAOKI H (Kumamoto Univ., Kumamoto) ,  SETOYAMA C (Kumamoto Univ., Kumamoto)
Material： Journal of Biochemistry  (J Biochem)
Volume： 134  Issue： 2  Page： 297-304  Publication year： Aug. 01, 2003 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *acyl-CoA dehydrogenase ,...
Semi thesaurus term： molecular model ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=03A0644886&from=J-GLOBAL&jstjournalNo=F0286A") }}

JST classification (1)： Enzyme in general  (EB09010D)

Substance index (4)： FAD ,  Lumiflavine ,  3S-C8-CoA ,  (Methylthio)acetic acid

Reference (24)：

• CRANE, F. L. On the mechanism of dehydrogenase of fatty acyl derivatives of coenzyme A. I. The general fatty acyl coenzyme A dehydrogenase. J. Biol. Chem. 1956, 218, 701-716
• ENGEL, P. C. Acyl-CoA dehydrogenases in Chemistry and Biochemistry of Flavoenzymes. 1992, III, 597-655
• KIM, J. J.-P. Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate. Proc. Natl Acad. Sci. USA. 1993, 15, 7523-7527
• GHISLA, S. Mechanistic studies with general acyl-CoA dehydrogenase and butyryl-CoA dehydrogenase : Evidence for the transfer of β-hydrogen to the flavin N(5)-position as hydride. Biochemistry. 1984, 23, 3154-3161
• LAU, S. M. The reductive half-reaction in Acyl-CoA dehydrogenase from pig kidney : studies with thiaoctanoyl-CoA and oxaoctanoyl-CoA analogues. Biochemistry. 1988, 27, 5089-5095

Terms in the title (9)： アシルCoAデヒドロゲナーゼ ,  遷移状態 ,  類縁体 ,  チア ,  オクタノイルCoA ,  電荷移動錯体 ,  結晶学 ,  分子軌道 ,  研究