Art

J-GLOBAL ID：200902250910911242   Reference number：09A1163764

A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH

非アルコール性脂肪性肝炎(NASH)の新規動物モデル 低酸素血症はNASH発症を亢進する

Author (8)： TAKAYAMA Fusako (Dep. of Clinical Pharmaceutical Sci., Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  EGASHIRA Toru (Dep. of Anti-Aging Food Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  KAWASAKI Hiromu (Dep. of Clinical Pharmaceutical Sci., Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  MANKURA Mitsumasa (Dep. of Anti-Aging Food Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  NAKAMOTO Kazuo (Dep. of Clinical Pharmaceutical Sci., Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  NAKAMOTO Kazuo (Dep. of Anti-Aging Food Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  OKADA Shigeru (Dep. of Anti-Aging Food Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.) ,  MORI Akitane (Dep. of Anti-Aging Food Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.)
Material： Journal of Clinical Biochemistry and Nutrition  (JCBN)
Volume： 45  Issue： 3  Page： 335-340 (J-STAGE)  Publication year： 2009 
JST Material Number： X0851A  ISSN： 0912-0009  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *hepatitis ,...
Semi thesaurus term： *Non-alcoholic steatohepatitis ,...

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JST classification (1)： Basic medicine on digestive system  (GH01020E)

Reference (20)：

• [1] Ludwig, J., Viggiano, T.R., McGill, D.B., and Ott, B.J.: Nonalcoholic steatohepatitis. Mayo clinic experiences with a hitherto unnamed disease. Mayo Clin. Proc., 55, 434–438, 1980.
• [2] Matteoni, C.A., Younossi, Z.M., Gramich, T., Boparai, N., Liu, Y.C., and McCullough, A.J.: Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology, 116, 1413–1419, 1999.
• [3] Kirsch, R., Clarkson, V., Shephard, E.G., Marais, D.A., Jaffer, M.A., Woodburne, V.E., Kirsch, R.E., and Hall Pde, L.: Rodent nutritional model of non-alcoholic steatohepatitis: Species, strain and sex difference studies. J. Gastroenterol. Hepatol., 18, 1272–1282, 2003.
• [4] Lieber, C.S., Leo, M.A., Mak, K.M., Xu, Y., Cao, Q., Ren, C., Ponomarenko, A., and DeCarli, L.M.: Model of nonalcoholic steatohepatitis. Am. J Clin. Nutr., 79, 502–509, 2004.
• [5] Feldstein, A.E., Canbay, A., Guicciardi, M.E., Higuchi, H., Bronk, S.F., and Gores, G.J.: Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. J. Hepatol., 39, 978–983, 2003.

Terms in the title (7)： 非アルコール性脂肪性肝炎 ,  NASH ,  動物 ,  モデル ,  低酸素血症 ,  発症 ,  亢進