Art

J-GLOBAL ID：200902252512559710   Reference number：04A0442983

Kigamicin D, a novel anticancer agent based on a new anti-austerity strategy targeting cancer cells’ tolerance to nutrient starvation

栄養素枯渇に対する癌細胞の耐性に標的化する新しい抗耐乏戦略に基づいた新しい抗癌剤,キガマイシンD

Author (5)： LU J (National Cancer Center Res. Inst. East, Chiba) ,  KUNIMOTO S (Inst. Microbial Chemistry, Tokyo) ,  YAMAZAKI Y (Inst. Microbial Chemistry, Tokyo) ,  KAMINISHI M (Univ. Tokyo, Tokyo) ,  ESUMI H (National Cancer Center Res. Inst. East, Chiba)
Material： Cancer Science  (Cancer Sci)
Volume： 95  Issue： 6  Page： 547-552  Publication year： Jun. 10, 2004 
JST Material Number： F0633A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antineoplastic antibiotics ,...
Semi thesaurus term： Actinomycetes ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y)

Substance index (1)： Kigamicin D

Reference (35)：

• SEMENZA, GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer. 2003, 3, 721-732
• ROCKWELL, S. Genomic Instability in cancer. Novartis Found Symp 2001. 2001, 240
• DANG, CV. Oncogenic alterations of metabolism. Trends Bio Sci. 1999, 24, 68-72
• PAPETTI, M. Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol. 2002, 282, C947-C970
• AEBERSOLD, DM. Angiogenesis as prognostic factor in malignant tumors. Ther Umsch. 1998, 55, 462-463

Terms in the title (8)： 栄養素 ,  枯渇 ,  癌細胞 ,  耐性 ,  標的化 ,  戦略 ,  抗癌剤 ,  キガマイシンD