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J-GLOBAL ID:200902252540929840   Reference number:06A0919741

Metabolic and Non-Metabolic Factors Determining Troglitazone Hepatotoxicity: A Review

トログリタゾン肝毒性を決定する代謝性と非代謝性因子:総説
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Volume: 21  Issue:Page: 347-356  Publication year: Oct. 30, 2006 
JST Material Number: X0758A  ISSN: 1347-4367  Document type: Article
Article type: 文献レビュー  Country of issue: Japan (JPN)  Language: ENGLISH (EN)
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Basic research of drugs acting on carbohydrate metabolism 
Reference (68):
  • 1) Watkins, P. B. and Whitcomb, R. W.: Hepatic dysfunction associated with troglitazone. N. Engl. J. Med., 338: 916-917 (1998).
  • 2) Gale, E. A.: Lessons from the glitazones: a story of drug development. Lancet, 357: 1870-1875 (2001).
  • 3) Graham, D. J., Green, L., Senior, J. R. and Nourjah, P.: Troglitazone-induced liver failure: a case study. Am. J. Med., 114: 299-306 (2003).
  • 4) Bissell, D. M., Gores, G. J., Laskin, D. L. and Hoofnagle, J. H.: Drug-induced liver injury: mechanisms and test systems. Hepatology, 33: 1009-1013 (2001).
  • 5) Smith, M. T.: Mechanisms of troglitazone hepatotoxicity. Chem. Res. Toxicol., 16: 679-687 (2003).
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