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J-GLOBAL ID：200902253799134729   Reference number：07A0216627

Cyclic Mechanical Strain Induces Interleukin-6 Expression via Prostaglandin E₂ Production by Cyclooxygenase-2 in MC3T3-E1 Osteoblast-like Cells

MC3T3-E1骨芽細胞様細胞において繰り返し機械的歪みがシクロオキシゲナーゼ-2によるプロスタグランジンE₂生成を介してインターロイキン-6発現を誘導する

Author (5)： NARUTOMI Masanori (Fukuoka Dental Coll., Fukuoka, JPN) ,  NISHIURA Toshihiro (Fukuoka Dental Coll., Fukuoka, JPN) ,  SAKAI Toshio (Fukuoka Dental Coll., Fukuoka, JPN) ,  ABE Kimio (Fukuoka Dental Coll., Fukuoka, JPN) ,  ISHIKAWA Hiroyuki (Fukuoka Dental Coll., Fukuoka, JPN)
Material： Journal of Oral Biosciences  (J Oral Biosci)
Volume： 49  Issue： 1  Page： 65-73  Publication year： Feb. 20, 2007 
JST Material Number： Y0018A  ISSN： 1349-0079  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *osteoblast ,...
Semi thesaurus term： Collagen Type I

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JST classification (2)： Basic medicine on musculoskeletal system  (GG01020B) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (2)： Dinoprostone ,  Indomethacin

Reference (37)：

• ROBERTS, W. E. Cellular response to orthodontic force. Dent. Clin. North Am. 1981, 25, 3-17
• RODAN, G. A. Gene expression in osteoblastic cells. Crit. Rev. Eukaryot. Gene. Expr. 1991, 1, 85-98
• MARTIN, T. J. Mechanisms by which cells of the osteoblast lineage control osteoclast formation and activity. J. Cell. Biochem. 1994, 56, 357-366
• KAJI, H. Prostaglandin E_2 stimulates osteoclast-like cell formation and bone-resorbing activity via osteoblasts : role of cAMP-dependent protein kinase. J. Bone Miner. Res. 1996, 11, 62-71
• MONTGOMERY, P. C. Evidence for the induction of two antibodies with identical combining sites in outbred animals. Nature. 1975, 256, 138-140

Terms in the title (8)： MC3T3-E1 ,  骨芽細胞様細胞 ,  機械的歪み ,  シクロオキシゲナーゼ-2 ,  プロスタグランジンE2 ,  インターロイキン-6 ,  発現 ,  誘導