Art

J-GLOBAL ID：200902253819841478   Reference number：05A0143540

Short-Step and Scalable Synthesis of (±)-Cytoxazone

(±)-サイトキサゾンの短工程で拡張可能な合成

Author (5)： ASANO M (Keio Univ., Yokohama, JPN) ,  NAGASAWA C (Keio Univ., Yokohama, JPN) ,  SUZUKI M (Keio Univ., Yokohama, JPN) ,  NISHIYAMA S (Keio Univ., Yokohama, JPN) ,  SUGAI T (Keio Univ., Yokohama, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 69  Issue： 1  Page： 145-148  Publication year： Jan. 23, 2005 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *bioactive factor ,...

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JST classification (1)： Cytokines  (EB08090G)

Substance index (3)： 4-Methoxycinnamyl alcohol ,  Acetonitrile ,  (-)-Cytoxazone

Reference (20)：

• 1) Kakeya, H., Morishita, M., Kobinata, K., Osono, M., Ishizuka, M., and Osada, H., Isolation and biological activity of a novel cytokine modulator, cytoxazone. J. Antibioics, 51, 1126–1128 (1998).
• 2) Kakeya, H., Morishita, M., Koshino, H., Morita, T., Kobayashi, K., and Osada, H., Cytoxazone: A novel cytokine modulator containing a 2-oxazolidinone ring produced by Streptomyces sp. J. Org. Chem., 64, 1052–1053 (1999).
• 3) Sakamoto, Y., Shiraishi, A., Seonhee, J., and Nakata, T., Stereoselective syntheses of cytoxazone, a novel cytokine modulator, and its stereoisomers. Tetrahedron Lett., 40, 4203–4206 (1999).
• 4) Seki, M., and Mori, K., Synthesis of (−)-cytoxazone, a novel modulator isolated from Streptomyces sp. Eur. J. Org. Chem., 2965–2967 (1999).
• 5) Park, J. N., Ko, S. Y., and Koh, H. Y., Synthetic application of the cyclic iminocarbonate rearrangement: enantioselective syntheses of chloamphenicol and 4-epi-cytoxazone. Tetrahedron Lett., 41, 5553–5556 (2000).

Terms in the title (2)： 短工程 ,  拡張