Art

J-GLOBAL ID：200902253931357520   Reference number：09A0052199

Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy

イマチニブ療法後の慢性骨髄性白血病における造血幹細胞でのBCR-ABL転写産物の維持ではあるが有意な低下

Author (12)： ABE Akihiro (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  MINAMI Yosuke (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  MINAMI Yosuke (Univ. California at San Diego School of Medicine, CA, USA) ,  HAYAKAWA Fumihiko (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  KITAMURA Kunio (Ichinomiya Municipal Hospital, Ichinomiya, JPN) ,  NOMURA Yuka (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  MURATA Makoto (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  KATSUMI Akira (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN) ,  KIYOI Hitoshi (Nagoya Univ. School of Medicine, Nagoya, JPN) ,  JAMIESON Catriona H.M. (Univ. California at San Diego School of Medicine, CA, USA) ,  WANG Jean Y.J. (Univ. California at San Diego School of Medicine, CA, USA) ,  NAOE Tomoki (Nagoya Univ. Graduate School of Medicine, Nagoya, JPN)
Material： International Journal of Hematology  (Int J Hematol)
Volume： 88  Issue： 5  Page： 471-475  Publication year： Dec. 2008 
JST Material Number： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  Document type： Article
Article type： 短報  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *chronic myeloid leukemia ,...
Semi thesaurus term： *BCR-ABL gene ,...

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JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Substance index (1)： imatinib mesilate

Reference (28)：

• SAWYERS, C. Targeted cancer therapy. Nature. 2004, 432, 294-297
• DRUKER, BJ. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med. 2006, 355, 2408-2417
• KANTARJIAN, HM. New strategies in chronic myeloid leukemia. Int J Hematol. 2006, 83, 289-293
• DEININGER, MW. Optimizing therapy of chronic myeloid leukemia. Exp Hematol. 2007, 35, 144-154
• SAVONA, M. Getting to the stem of chronic myeloid leukaemia. Nat Rev Cancer. 2008, 8, 341-350

Terms in the title (6)： イマチニブ ,  療法 ,  慢性骨髄性白血病 ,  造血幹細胞 ,  BCR-ABL ,  転写産物