Art

J-GLOBAL ID：200902254245274045   Reference number：09A0411682

Transformation from follicular lymphoma to high-grade B-cell lymphoma/leukemia with additional t(2;8)(p12;q24), with inverse expressions of c-MYC and BCL-2, and light-chain switch

t(2;8)(p12;q24),c-MYCとBCL-2の逆現象,そして軽鎖変化を伴った濾胞性リンパ腫から高悪性度B細胞リンパ腫/白血病への病変

Author (10)： MANNOUJI Kiyohito (Kawasaki Medical School, Kurashiki, JPN) ,  TASAKA Taizo (Kawasaki Medical School, Kurashiki, JPN) ,  AKIYAMA Takashi (Kawasaki Medical School, Kurashiki, JPN) ,  IREI Isao (Kawasaki Medical School, Kurashiki, JPN) ,  SANO Fuminori (Kawasaki Medical School, Kurashiki, JPN) ,  MATSUHASHI Yoshiko (Kawasaki Medical School, Kurashiki, JPN) ,  WADA Hideho (Kawasaki Medical School, Kurashiki, JPN) ,  TOHYAMA Kaoru (Kawasaki Medical School, Kurashiki, JPN) ,  SUGIHARA Takashi (Kawasaki Medical School, Kurashiki, JPN) ,  SADAHIRA Yoshito (Kawasaki Medical School, Kurashiki, JPN)
Material： Pathology International  (Pathol Int)
Volume： 59  Issue： 4  Page： 261-264  Publication year： Apr. 2009 
JST Material Number： W0853A  ISSN： 1320-5463  Document type： Article
Article type： 短報  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： BCL-2 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=09A0411682&from=J-GLOBAL&jstjournalNo=W0853A") }}

JST classification (2)： Blood cell tumors(=neoplasms)  (GK04000M) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Substance index (4)： Etoposide ,  Cyclophosphamid ,  Cytarabine ,  Dexamethasone

Reference (18)：

• HOCKENBERRY, D. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 1990, 348, 334-336
• MCDONNELL, TJ. Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature. 1991, 349, 254-256
• YUNIS, JJ. Multiple recurrent genomic defects in follicular lymphoma : A possible model for cancer. N Engl J Med. 1987, 316, 79-84
• TILLY, H. Prognostic value of chromosomal abnormalities in follicular lymphoma. Blood. 1994, 84, 1043-1049
• HORSMAN, DE. Analysis of secondary chromosomal alterations in 165 cases of follicular lymphoma with t(14:18). Genes Chromosomes Cancer. 2001, 30, 375-382

Terms in the title (6)： 現象 ,  軽鎖 ,  濾胞性リンパ腫 ,  高悪性度B細胞リンパ腫 ,  白血病 ,  病変