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J-GLOBAL ID：200902254498500742   Reference number：09A0383111

Novel Function of Transcription Factor ATF5: Blockade of p53-dependent Apoptosis Induced by Ionizing Irradiation

転写因子ATF5の新規機能:電離照射により誘導されるp53依存性アポトーシスの遮断

Author (8)： NISHIOKA Takeshi (Dep. of Biomedical Sciences and Engineering, Fac. of Health Sciences, Graduate School of Health Sciences, Hokkaido Univ.) ,  MIYAI Yusuke (Div. of Biological Sciences, Graduate School of Sci., Hokkaido Univ.) ,  HAGA Hisashi (Div. of Biological Sciences, Graduate School of Sci., Hokkaido Univ.) ,  KAWABATA Kazushige (Div. of Biological Sciences, Graduate School of Sci., Hokkaido Univ.) ,  SHIRATO Hiroki (Dep. of Radiology, Graduate School of Medicine, Hokkaido Univ.) ,  HOMMA Akihiro (Dep. of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Hokkaido Univ.) ,  SHIBATA Kenichiro (Dep. of Oral Pathobiology, Graduate School of Dental Medicine, Hokkaido Univ.) ,  YASUDA Motoaki (Dep. of Oral Pathobiology, Graduate School of Dental Medicine, Hokkaido Univ.)
Material： Cell Structure and Function  (Cell Struct Funct)
Volume： 34  Issue： 1  Page： 17-22 (J-STAGE)  Publication year： 2009 
JST Material Number： Y0044A  ISSN： 0386-7196  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *transcription factor ,...
Semi thesaurus term： QRsP細胞

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JST classification (3)： Cell physiology in general  (EF02010S) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Influence on cellular levels  (EK02030D)

Reference (15)：

• Angelastro, J.M., Canoll, P.D., Kuo, J., Weicker, M., Costa, A., Bruce, J.N., and Greene, L.A. 2006. Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5. Oncogene, 25: 907–916.
• Barbieri, C.E., Tang, L.J., Brown, K.A., and Pietenpol, J.A. 2006. Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis. Cancer Res., 66: 7589–7597.
• Flores, E.R., Tsai, K.Y., Crowley, D., Sengupta, S.,Yang, A., McKeon F., and Jacks, T. 2002. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature, 416: 560–564.
• Greenblatt, M.S., Bennett, W.P., Hollstein M., and Harris C.C. 1994. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855–4878.
• Hai, T. and Hartman, M.G. 2001. The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene, 273: 1–11.

Terms in the title (8)： 転写因子 ,  ATF5 ,  電離 ,  誘導 ,  p53 ,  依存性 ,  アポトーシス ,  遮断