Art

J-GLOBAL ID：200902254499495211   Reference number：05A0300561

Effects of AF-DX116 and Other Muscarinic Receptor Antagonists on Orthostatic Hypotension in Autonomic Imbalanced (SART-Stressed) Rats

自律神経失調症(SART-ストレス)ラットでの起立性低血圧症に及ぼすAF-DX116や他のムスカリン受容体きっ抗薬の作用

Author (3)： HATA T (Kinki Univ., Higashi-Osaka, JPN) ,  FUNAKAMI Y (Kinki Univ., Higashi-Osaka, JPN) ,  ITOH E (Kinki Univ., Higashi-Osaka, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 97  Issue： 3  Page： 386-392  Publication year： Mar. 20, 2005 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *autonomic imbalance ,...
Semi thesaurus term： bridged compound ,...

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JST classification (3)： Nervous system in general  (EJ12010J) ,  Basic medicine on cardiovascular system  (GJ01020K) ,  Basic research of parasympathetics  (GW05032S)

Substance index (5)： AF-DX-116 ,  Methoctramine ,  Atropine ,  Methylatropine ,  Pirenzepine

Reference (25)：

• 1 Klingenheben T. Autonomic dysfunction and orthostatic intolerance. Internist (Berl). 2002;43:1055–1064.
• 2 Dobkin BH. Orthostatic hypotension as a risk factor for symptomatic occlusive cerebrovascular disease. Neurology. 1989;39:30–34.
• 3 Grubb BP, Karas B. Clinical disorders of the autonomic nervous system associated with orthostatic intolerance: an overview of classification, clinical evaluation, and management. Pacing Clin Electrophysiol. 1999;22:798–810.
• 4 Kita T, Hata T, Yoneda R, Okage T. Stress state caused by alternation of rhythms in environmental temperature, and the functional changes in mice and rats. Folia Pharmaco Jpn (Nippon Yakurigaku Zasshi). 1975;71:195–210. (text in Japanese with English abstract)
• 5 Kita T, Hata T, Itoh E, Namimatsu A. Testing methods for vegetative syndrome in the rat and effects of Neurotropin and other drugs. Jpn J Psychosom Med. 1983;23:61–68.

Terms in the title (6)： 自律神経失調症 ,  ストレス ,  ラット ,  起立性低血圧症 ,  AF ,  ムスカリン受容体きっ抗薬