Art

J-GLOBAL ID：200902255178721666   Reference number：09A0143668

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

全ゲノム関連研究が高血圧感受性遺伝子としてSTK39を同定する

Author (22)： WANG Ying (Univ. Maryland School of Medicine, MD) ,  O'CONNELL Jeffrey R. (Univ. Maryland School of Medicine, MD) ,  MCARDLE Patrick F. (Univ. Maryland School of Medicine, MD) ,  WADE James B. (Univ. Maryland School of Medicine, MD) ,  DORFF Sarah E. (Univ. Maryland School of Medicine, MD) ,  SHAH Sanjiv J. (Univ. Chicago, IL) ,  SHI Xiaolian (Univ. Maryland School of Medicine, MD) ,  PAN Lin (Univ. Chicago, IL) ,  RAMPERSAUD Evadnie (Univ. Maryland School of Medicine, MD) ,  SHEN Haiqing (Univ. Maryland School of Medicine, MD) ,  KIM James D. (Georgetown Univ. School of Medicine, Washington, DC) ,  SUBRAMANYA Arohan R. (Univ. Maryland School of Medicine, MD) ,  STEINLE Nanette I. (Univ. Maryland School of Medicine, MD) ,  PARSA Afshin (Univ. Maryland School of Medicine, MD) ,  OBER Carole C. (Univ. Chicago, IL) ,  WELLING Paul A. (Univ. Maryland School of Medicine, MD) ,  CHAKRAVARTI Aravinda (Johns Hopkins Univ. School of Medicine, MD) ,  WEDER Alan B. (Univ. Maryland School of Medicine, MD) ,  COOPER Richard S. (Loyola Stritch School of Medicine, IL) ,  MITCHELL Braxton D. (Univ. Maryland School of Medicine, MD) ,  SHULDINER Alan R. (Univ. Maryland School of Medicine, MD) ,  CHANG Yen-Pei C. (Univ. Maryland School of Medicine, MD)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 106  Issue： 1  Page： 226-231  Publication year： Jan. 06, 2009 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,  genome ,  blood pressure ,  systolic blood pressure ,  gene ,  serine-threonine kinase ,  *single nucleotide polymorphism ,  nephron ,  gene expression ,  biodistribution ,  *essential hypertension ,  ion pump(organism) ,  nucleotide sequence ,  homology(characteristic)
Semi thesaurus term： SPAK ,  STK3遺伝子 ,  WNK kinase ,  Sodium Chloride Symporters ,  遠位ネフロン ,  diastolic blood pressure

JST classification (2)： Genetic variation  (EC01030Y) ,  Congenital diseases,deformities in general.  (GD03010V)

Terms in the title (5)： ゲノム ,  研究 ,  血圧 ,  感受性遺伝子 ,  同定