Art

J-GLOBAL ID：200902256522820888   Reference number：04A0880084

Toll-Like Receptor-Targeting Immunotherapy for Oral Cancer

口腔癌に対するToll様受容体標的化免疫治療

Author (2)： OKAMOTO M (Tokushima Univ. School of Dentistry) ,  SATO M (Tokushima Univ. School of Dentistry)
Material： Oral Science International  (Oral Sci Int)
Volume： 1  Issue： 1  Page： 1-15  Publication year： May. 2004 
JST Material Number： L5012A  ISSN： 1348-8643  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *mouth tumor ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (3)： Tumors(=neoplasms)of tooth and mouth(=oral cavity)  (GT04000N) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Reference (64)：

• 1. Okamoto H., Shoin S., Koshimura S., and Shimizu R.: Studies on the anticancer and streptolysin S-forming abilities of hemolytic streptococci. Jpn J Microbiol 11: 323-336, 1967.
• 2. Maehara Y., Okuyama T., Kakeji Y., Baba H., Furusawa M., and Sigimachi K.: Postoperative immunochemo-therapy including streptococcal lysate OK-432 is effective for patients with gastric cancer and serosal invasion. Am J Surg 168: 36-40, 1994.
• 3. Kitahara S., Ikeda M., Inoue T., Matsunaga T., Yamaguchi K., Takayama E., Healy G.B., and Tsukuda M.: Inhibition of head and neck metastatic and/or recurrent cancer by local administration of multi-cytokine inducer OK-432. J Laryngol Otol 110: 449-453, 1996.
• 4. Sato M., Harada K., Yoshida H., Yura Y., Azuma M., Iga H., Bando T., Kawamata H., and Takegawa Y.: Therapy for oral squamous cell carcinoma by tegafur and streptococcal agent OK-432 in combination with radiotherapy: Association of the therapeutic effect with differentiation and apoptosis in the cancet cells. Apoptosis 2: 227-238, 1997.
• 5. Okamoto M., Oshikawa T., Tano T., Ohe G., Furuichi S., Nishikawa H., Ahmed SU., Akashi S., Miyake K., Takeuchi O., Akira S., Moriya Y., Matsubara S., Ryoma Y., Saito M., and Sato M.: Involvement of Toll-like receptor 4 signaling in interferon-γproduction and anti-tumor effect by a streptococcal agent OK-432. J Natl Cancer Inst 95: 316-326, 2003.

Terms in the title (4)： 口腔癌 ,  Toll様受容体 ,  標的化 ,  免疫治療