Art

J-GLOBAL ID：200902256562468826   Reference number：07A0129384

Gene Analyses of Genetic Abnormalities of Scurvy-prone Animals

壊血病発症動物における遺伝子異常の解析

Author (1)： NISHIKIMI MORIMITSU (和歌山県医大 医 生化学)
Material： ビタミン  (Vitamins)
Volume： 81  Issue： 1  Page： 1-8  Publication year： Jan. 25, 2007 
JST Material Number： F0426A  ISSN： 0006-386X  CODEN： BTMNA7  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *scurvy ,...
Semi thesaurus term： genetic disorder ,...

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JST classification (2)： Vitamin C  (EB07040W) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (1)： Ascorbic Acid

Reference (35)：

• BURNS, JJ. Metabolic Pathways. 1960, 1, 341-356
• NISHIKIMI, M. Guinea pigs possess a highly mutated gene for L-gulono-γ-lactone oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in this species. J Biol Chem. 1992, 267, 21967-21972
• NISHIKIMI, M. Cloning and chromosomal mapping of the human nonfunctional gene for L-gulono-γ-lactone oxidase, the enzyme for L-ascorbic acid biosynthesis missing in man. J Biol Chem. 1994, 269, 13685-13688
• KAWAI, T. A missense mutation of L-gulono-γ-lactone oxidase causes the inability of scurvy-prone osteogenic disorder rats to synthesize L-ascorbic acid. J Biol Chem. 1992, 267, 21973-21976
• NISHIKIMI, M. Identification by bacterial expression of the yeast genomic sequence encoding L-galactono-γ-lactone oxidase, the homologue of L-ascorbic acid-synthesizing enzyme of higher animals. Biochem Mol Biol Int. 1998, 44, 907-913

Terms in the title (5)： 壊血病 ,  発症 ,  動物 ,  遺伝子異常 ,  解析