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J-GLOBAL ID：200902257250737915   Reference number：05A0760084

A FACILE METHOD FOR CONVERSION OF PHENOLIC TETRAHYDROISOQUINOLINES TO BENZYLAMINES WITH RING CLEAVAGE

フェノール性テトラヒドロイソキノリン類の環開裂を伴うベンジルアミン類への容易な変換法

Author (8)： NAKATA Takashi (Tokyo Univ. Sci., Chiba, JPN) ,  KOMATSU Naho (Tokyo Univ. Sci., Chiba, JPN) ,  YAMANAKA Mamiko (Tokyo Univ. Sci., Chiba, JPN) ,  LEE Hae Joo (Tokyo Univ. Sci., Chiba, JPN) ,  MATSUOKA Yutaka (Tokyo Univ. Sci., Chiba, JPN) ,  NISHITANI Kiyoshi (Tokyo Univ. Sci., Chiba, JPN) ,  ISHIZAKI Miyuki (Tokyo Univ. Sci., Chiba, JPN) ,  HARA Hiroshi (Tokyo Univ. Sci., Chiba, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 65  Issue： 9  Page： 2057-2060  Publication year： Sep. 01, 2005 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...

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JST classification (3)： Quinolines,isoquinolines  (CF07096H) ,  Aromatic monocyclic amine,imine,quaternary ammonium,immonium compounds  (CF05050D) ,  Cyclization reaction,ring-opening reaction  (CF02050I)

Substance index (18)： Morpholine ,  Piperidine ,  1-Methylpiperazine ,  1-Phenylpiperazine ,  2-Methyl-2-(cyanomethyl)-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinolinium・iodide ,  2-Methyl-2-(cyanomethyl)-4-phenyl-8-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinolinium・iodide ,  2-Methyl-2-(cyanomethyl)-6-hydroxy-1,2,3,4-tetrahydroisoquinolinium・iodide ,  2-Methyl-2-(cyanomethyl)-4-phenyl-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinolinium・iodide ,  1,2-Dimethyl-2-(cyanomethyl)-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinolinium・iodide ,  [Methyl[2-(morpholinomethyl)-4-methoxy-5-hydroxyphenethyl]amino]acetonitrile ,  [Methyl[2-(piperidinomethyl)-4-methoxy-5-hydroxyphenethyl]amino]acetonitrile ,  [Methyl[2-(4-methylpiperazinomethyl)-4-methoxy-5-hydroxyphenethyl]amino]acetonitrile ,  [Methyl[β-phenyl-2-(morpholinomethyl)-3-hydroxy-4-methoxyphenethyl]amino]acetonitrile ,  [Methyl[β-phenyl-2-(piperidinomethyl)-3-hydroxy-4-methoxyphenethyl]amino]acetonitrile ,  [Methyl[2-(morpholinomethyl)-5-hydroxyphenethyl]amino]acetonitrile ,  [Methyl[2-(piperidinomethyl)-5-hydroxyphenethyl]amino]acetonitrile ,  [Methyl[β-phenyl-2-(morpholinomethyl)-4-methoxy-5-hydroxyphenethyl]amino]acetonitrile ,  [Methyl[2-[1-(4-phenylpiperazino)ethyl]-4-methoxy-5-hydroxyphenethyl]amino]acetonitrile

Terms in the title (4)： フェノール ,  テトラヒドロイソキノリン類 ,  環開裂 ,  ベンジルアミン類