Art

J-GLOBAL ID：200902257666999617   Reference number：03A0267243

Mushroom Tyrosinase Inhibitory Activity of Esculetin Isolated from Seeds of Euphorbia lathyris L.

トウダイグサ(Euphorbia lathyris)の種子から分離したエスクレチンのマッシュルームチロシナーゼ阻害活性

Author (6)： MASAMOTO Y (Okayama Univ., Okayama, JPN) ,  ANDO H (Sunstar Inc., Osaka, JPN) ,  MURATA Y (Sunstar Inc., Osaka, JPN) ,  SHIMOISHI Y (Sunstar Inc., Osaka, JPN) ,  TADA M (Okayama Univ., Okayama, JPN) ,  TAKAHATA K (Sunstar Inc., Osaka, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 67  Issue： 3  Page： 631-634  Publication year： Mar. 23, 2003 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： mushroom ,...
Semi thesaurus term： monophenol oxidase ,...

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JST classification (2)： Enzyme in general  (EB09010D) ,  Microorganism biochemistry  (EG03020N)

Substance index (5)： Esculetin ,  Coumarin ,  7-Hydroxycoumarin ,  Esculin ,  Scopoletin

Reference (29)：

• 1) Hearing, V. J., and Jiménez, M., Mammalian tyrosinase: The critical regulatory control point in melanocyte pigmentation. Int. J. Biochem., 19, 1141-1147 (1987).
• 2) Jiménez, M., Tsukamoto, K., and Hearing, V. J., Tyrosinase from two different loci are expressed by normal and by transformed melanocytes. J. Biol. Chem., 266, 1147-1156 (1991).
• 3) Tsukamoto, K., Jackson, I. J., Urabe, K., Montague, P. M., and Hearing, V. J., A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPA-chrome tautomerase. EMBO J., 11, 519-526 (1992).
• 4) Jiménez-Cervantes, C., Solano, F., Kobayashi, T., Urabe, K., Hearing, V. J., and Garcia-Borron, J. C., A new enzymatic function in the melanogenic pathway. J. Biol. Chem., 269, 17993-18001 (1994).
• 5) Hashimoto, A., Ichihashi, M., and Mishima, Y., The mechanism of depigmentation by hydroquinone; a study on suppression and recovery processes of tyrosinase activity in the pigment cells in vivo and in vitro. Jpn. J. Dermatol., 94, 794-804 (1984).

Terms in the title (5)： Euphorbia ,  種子 ,  エスクレチン ,  マッシュルーム ,  チロシナーゼ阻害活性