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J-GLOBAL ID：200902257791913252   Reference number：04A0423184

Correlation between the Catalase Level in Tumor Cells and Their Sensitivity to N-β-Alanyl-5-S-Glutathionyl-3,4-Dihydroxyphenylalanine (5-S-GAD)

腫よう細胞におけるカタラーゼレベルとN-β-アラニル-5-S-グルタチオニル-3,4-ジヒドロキシフェニルアラニン(5-S-GAD)に対するこれらの感受性の間の相関

Author (4)： NISHIKAWA T (Inst. of Physical and Chemical Res. (RIKEN), Saitama) ,  NISHIKAWA S (Inst. of Physical and Chemical Res. (RIKEN), Saitama) ,  AKIYAMA N (Inst. of Physical and Chemical Res. (RIKEN), Saitama) ,  NATORI S (Inst. of Physical and Chemical Res. (RIKEN), Saitama)
Material： Journal of Biochemistry  (J Biochem)
Volume： 135  Issue： 4  Page： 465-469  Publication year： Apr. 01, 2004 
JST Material Number： F0286A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： tumor cell ,...
Semi thesaurus term： RNAi

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JST classification (2)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y) ,  Enzyme in general  (EB09010D)

Substance index (1)： 5-S-GAD

Reference (20)：

• LEEM, J. Y. Purification and characterization of N-β-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine, a novel antibacterial substance of Sarcophaga peregrina (flesh fly). J. Biol. Chem. 1996, 271, 13573-13577
• AKIYAMA, N. Anti-tumor effect of N-β-alanyl-5-S-glutathionyldihydroxyphenylalanine (5-S-GAD), a novel antibacterial substance from an insect. Anticancer Res. 2000, 20, 357-362
• HIJIKATA, M. Induction of apoptosis of monocytemacrophage lineage cells by 5-S-GAD. FEBS Lett. 1999, 457, 405-408
• HIJIKATA, M. Inhibition of protein tyrosine kinase by 5-S-GAD, a novel antibacterial substance from an insect. Biochem. Biophys. Res. Commun. 1997, 237, 423-426
• LEEM, J. Y. Inhibitory effects of 5-S-GAD on phosphorylation of V-SRC and BCR-ABL tyrosine kinase. Biol. Pharm. Bull. 1998, 21, 784-785

Terms in the title (6)： 腫よう細胞 ,  カタラーゼ ,  ジヒドロキシフェニルアラニン ,  5-S-GAD ,  感受性 ,  相関