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J-GLOBAL ID：200902257949764845   Reference number：04A0066039

Kigamicins, Novel Antitumor Antibiotics: II. Structure Determination

Kigamicins,新しい抗腫よう抗生物質 2.構造決定

Author (6)： KUNIMOTO S (Numazu Bio-Medical Res. Inst., Shizuoka, JPN) ,  SOMENO T (Numazu Bio-Medical Res. Inst., Shizuoka, JPN) ,  YAMAZAKI Y (Numazu Bio-Medical Res. Inst., Shizuoka, JPN) ,  LU J (National Cancer Center Res. Inst. East, Chiba, JPN) ,  ESUMI H (National Cancer Center Res. Inst. East, Chiba, JPN) ,  NAGANAWA H (Numazu Bio-Medical Res. Inst., Shizuoka, JPN)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 56  Issue： 12  Page： 1012-1017  Publication year： Dec. 25, 2003 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antineoplastic antibiotics ,...
Semi thesaurus term： Kigamicins ,...

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JST classification (2)： Antibiotics in general  (GX01000E) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (5)： Kigamicin A ,  Kigamicin B ,  Kigamicin C ,  Kigamicin D ,  Kigamicin E

Reference (7)：

• 1) KUNIMOTO, S.; J. LU, H. ESUMI, Y. YAMAZAKI, N. KINOSHITA, Y. HONMA, M. HAMADA, M. OHSONO, M. ISHIZUKA & T. TAKEUCHI: Kigamicins, novel antitumor antibiotics. I. Taxonomy, isolation, physico-chemical properties and biological activities. J. Antibiotics 56: 1004-1011, 2003
• 2) LU, J.; S. KUNIMOTO, Y. YAMAZAKI, M. KAMINISHI & H. ESUMI; Kigamicin D, a novel anti-cancer agent based on a new strategy; Anti-Austerity, be submitted, 2003
• 3) CHU, M.; I. TRUUMEES, R. MIERZAWA, J. TERRACCIANO, M. PATEL, D. LOEBENBERG, J. J. KAMINSK, P. DAS & M. S. PUAR: Sch 54445; A new polycyclic xanthone with highly potent antifungal activity produced by Actinoplanes sp. J. Nat. Prod., 60: 525-528, 1997
• 4) NAKAGAWA, A.; S. OMURA, K. KUSIDA, H. SHIMIZU & G. LUKACS: Structure of cervinomycin, a novel xanthone antibiotic active against anaerobe and mycoplasma. J. Antibiotics 40: 301-319, 1987
• 5) KOBAYASHI, K.; C. NISHINO, J. OHYA, S. SATO, T. MIKAWA, Y. SHIOBARA & M. KODAMA: Actinoplanones, C, D, E, F and G, new cytotoxic polycyclic xanthones from Actinoplanes sp. J. Antibiotics 41: 741-750, 1988

Terms in the title (1)： 抗腫よう抗生物質