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J-GLOBAL ID：200902258949160903   Reference number：08A0917957

Hepatocyte growth factor gene transfer with naked plasmid DNA ameliorates dimethylnitrosamine-induced liver fibrosis in rats

nakedプラスミドDNAによる肝細胞増殖因子遺伝子導入はラットにおけるジメチルニトロソアミン誘導性肝線維症を改善させる

Author (8)： KANEMURA Hironari (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  IIMURO Yuji (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  TAKEUCHI Masaharu (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  UEKI Takahiro (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  HIRANO Tadamichi (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  HORIGUCHI Kiyoshi (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  ASANO Yasukane (Hyogo Coll. of Medicine, Nishinomiya, JPN) ,  FUJIMOTO Jiro (Hyogo Coll. of Medicine, Nishinomiya, JPN)
Material： Hepatology Research  (Hepatol Res)
Volume： 38  Issue： 9  Page： 930-939  Publication year： Sep. 2008 
JST Material Number： W1284A  ISSN： 1386-6346  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *naked DNA法 ,...

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JST classification (3)： Research methods in zoology  (EJ01020I) ,  Liver  (EJ06060J) ,  Gene manipulation  (EC02050B)

Reference (38)：

• FRIEDMAN, SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem. 2000, 275, 2247-2250
• PINZANI, M. Progression of fibrosis in chronic liver diseases : time to tally the score. J Hepatol. 2001, 34, 764-767
• MIYAZAWA, K. Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. Biochem Biophys Res Commun. 1989, 163, 967-973
• NAKAMURA, T. Molecular cloning and expression of human hepatocyte growth factor. Nature. 1989, 342, 440-443
• NAKAMURA, T. Structure and function of hepatocyte growth factor. Prog Growth Factor Res. 1991, 3, 67-85

Terms in the title (5)： プラスミドDNA ,  肝細胞増殖因子遺伝子 ,  ラット ,  ジメチルニトロソアミン ,  肝線維症