Art

J-GLOBAL ID：200902259710656806   Reference number：07A0018402

Differential Impact of Atorvastatin vs Pravastatin on Progressive Insulin Resistance and Left Ventricular Diastolic Dysfunction in a Rat Model of Type II Diabetes

II型糖尿病のラットモデルにおける進行性インシュリン耐性および左心室拡張期機能不全に与えるアトルバスタチン対プラバスタチンの異なる効果

Author (9)： CHEN Yan (Dep. of Cardiorenal Cerebrovascular Medicine, Kagawa Univ. School of Medicine) ,  OHMORI Koji (Dep. of Cardiorenal Cerebrovascular Medicine, Kagawa Univ. School of Medicine) ,  MIZUKAWA Mizuki (Dep. of Cardiorenal Cerebrovascular Medicine, Kagawa Univ. School of Medicine) ,  YOSHIDA Junji (Dep. of Cardiorenal Cerebrovascular Medicine, Kagawa Univ. School of Medicine) ,  ZENG Yu (Dep. of Urology, Kagawa Univ. School of Medicine) ,  ZHANG Ling (Dep. of Cardiovascular Physiology, Kagawa Univ. School of Medicine) ,  SHINOMIYA Kaori (Dep. of Cardiorenal Cerebrovascular Medicine, Kagawa Univ. School of Medicine) ,  KOSAKA Hiroaki (Dep. of Cardiovascular Physiology, Kagawa Univ. School of Medicine) ,  KOHNO Masakazu (Dep. of Cardiorenal Cerebrovascular Medicine, Kagawa Univ. School of Medicine)
Material： Circulation Journal  (Circ J)
Volume： 71  Issue： 1  Page： 144-152 (J-STAGE)  Publication year： 2007 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Rattus ,...
Semi thesaurus term： non-insulin-dependent diabetes mellitus ,...

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JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (2)： Pravastatin ,  Atorvastatin

Reference (41)：

• 1. Devereux RB, Roman MJ, Paranicas M, O'Grady MJ, Lee ET, Welty TK, et al. Impact of diabetes on cardiac structure and function: The strong heart study. Circulation 2000; 101: 2271-2276.
• 2. Hayden MR, Tyagi SC. Myocardial redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and congestive heart failure. Med Sci Monit 2003; 9: SR35-SR52.
• 3. Kosuge M, Kimura K, Ishikawa T, Shimizi T, Hibi K, Toda N, et al. Persistent hyperglycemia is associated with left ventricular dysfunction in patients with acute myocardial infarction. Circ J 2005; 69: 23-28.
• 4. Yu Y, Ohmori K, Kondo I, Yao L, Noma T, Tsuji T, et al. Correlation of functional and structural alterations of the coronary arterioles during development of type II diabetes mellitus in rats. Cardiovasc Res 2002; 56: 303-311.
• 5. Mizushige K, Yao L, Noma T, Kiyomoto H, Yu Y, Hosomi N, et al. Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat model. Circulation 2000; 101: 899-907.

Terms in the title (8)： II型糖尿病 ,  ラット ,  モデル ,  インシュリン耐性 ,  左心室拡張 ,  機能不全 ,  アトルバスタチン ,  プラバスタチン