Art

J-GLOBAL ID：200902259716796030   Reference number：09A0593251

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

進行した前立腺癌の治療のための第二世代抗アンドロゲン剤の発展

Author (20)： TRAN Chris (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  OUK Samedy (Univ. California Los Angeles, CA, USA) ,  CLEGG Nicola J. (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  CHEN Yu (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  WATSON Philip A. (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  ARORA Vivek (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  WONGVIPAT John (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  SMITH-JONES Peter M. (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  YOO Dongwon (Univ. California Los Angeles, CA, USA) ,  KWON Andrew (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  WASIELEWSKA Teresa (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  WELSBIE Derek (Univ. California Los Angeles, CA, USA) ,  CHEN Charlie Degui (Univ. California Los Angeles, CA, USA) ,  HIGANO Celestia S. (Univ. Washington, WA, USA) ,  BEER Tomasz M. (Oregon Health and Sci. Univ., OR, USA) ,  HUNG David T. (Medivation, Inc., CA, USA) ,  SCHER Howard I. (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  JUNG Michael E. (Univ. California Los Angeles, CA, USA) ,  SAWYERS Charles L. (Memorial Sloan-Kettering Cancer Center, NY, USA) ,  SAWYERS Charles L. (Howard Hughes Medical Inst., NY, USA)
Material： Science
Volume： 324  Issue： 5928  Page： 787-790  Publication year： May. 08, 2009 
JST Material Number： E0078A  ISSN： 0036-8075  CODEN： SCIEA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *prostatic tumor ,  neoplasm staging ,  *Hormone Antagonists ,  therapy ,  pharmacokinetics ,  laboratory animal ,  *prostate-specific antigen ,  serum concentration ,  androgen receptor ,  affinity ,  Models, Animal ,  binding affinity ,  *Androgen Antagonists
Semi thesaurus term： *anti-androgen ,  pharmacokinetics ,  バイカルタミド

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Urogenital tumors(=neoplasms)  (GM04000S)

Substance index (1)： Thiohydantoin

Terms in the title (5)： 前立腺癌 ,  治療 ,  世代 ,  抗アンドロゲン剤 ,  発展