Art

J-GLOBAL ID：200902259815458023   Reference number：05A0355777

PKC theta, a novel immunohistochemical marker for gastrointestinal stromal tumors (GIST), especially useful for identifying KIT-negative tumors

消化管間質腫よう(GIST)の新規免疫組織化学マーカーであるPKCθはKIT陰性腫ようの同定に特に有用である

Author (6)： MOTEGI Atsushi (Gunma Univ., Gunma, JPN) ,  SAKURAI Shinji (Jichi Medical School, Tochigi, JPN) ,  NAKAYAMA Hiroko (Gunma Univ., Gunma, JPN) ,  SANO Takaaki (Gunma Univ., Gunma, JPN) ,  OYAMA Tetsunari (Gunma Univ., Gunma, JPN) ,  NAKAJIMA Takashi (Gunma Univ., Gunma, JPN)
Material： Pathology International  (Pathol Int)
Volume： 55  Issue： 3  Page： 106-112  Publication year： Mar. 2005 
JST Material Number： W0853A  ISSN： 1320-5463  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： thymus tumor ,...

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JST classification (4)： Diagnosis of tumors(=neoplasms)  (GE03020J) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Enzyme in general  (EB09010D) ,  Gene expression  (EC02040Q)

Reference (43)：

• ROSAI, J. Gastrointestinal tract. Ackerman's Surgical Pathology. 1996, 645-647
• FLETCHER, CD. Diagnosis of gastrointestinal stromal tumors : a consensus approach. Hum Pathol. 2002, 33, 459-465
• MIETTINEN, M. Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001, 438, 1-12
• HIROTA, S. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 1998, 279, 577-580
• KINDBLOM, LG. Gastrointestinal pacemaker cell tumor (GIPACT) : gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol. 1998, 152, 1259-1269

Terms in the title (8)： 消化管間質腫よう ,  GIST ,  免疫組織化学 ,  マーカー ,  PKCθ ,  KIT ,  腫よう ,  同定