Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking

KUNITA R; OTOMO A; MIZUMURA H; SUZUKI K; SHOWGUCHI-MIYATA J; YANAGISAWA Y; HADANO S; IKEDA J

Art

J-GLOBAL ID：200902259829466371 Reference number：04A0743353

Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking

独特のカルボキシル端末領域を通じたALS2のホモ-オリゴマ化はALS2会合Rab5グアニンヌクレオチド交換活性とエンドソーム輸送に対するその調節機能にとって必須である。

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Material：
Volume： 279 Issue： 37 Page： 38626-38635 Publication year： Sep. 10, 2004
JST Material Number： E0038A ISSN： 0021-9258 CODEN： JBCHA3 Document type： Article
Article type：原著論文 Country of issue： United States (USA) Language： ENGLISH (EN)

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Biological function , Cell physiology in general , Congenital diseases,deformities in general.

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