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J-GLOBAL ID：200902260467398125   Reference number：05A0781293

Combinatorial Synthesis of MUC1 Glycopeptides: Polymer Blotting Facilitates Chemical and Enzymatic Synthesis of Highly Complicated Mucin Glycopeptides

MUC1糖ペプチドのコンビナトリアル合成 ポリマーブロッティングは高度に複雑なムチン糖ペプチドの化学的および酵素的合成を容易にする

Author (14)： FUMOTO Masataka (Res. Assoc. for Biotechnology, Tokyo, JPN) ,  FUMOTO Masataka (Shionogi & Co. Ltd., Osaka, JPN) ,  HINOU Hiroshi (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Sapporo, JPN) ,  OHTA Takashi (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Sapporo, JPN) ,  ITO Takaomi (Shionogi & Co. Ltd., Osaka, JPN) ,  YAMADA Kuriko (Res. Assoc. for Biotechnology, Tokyo, JPN) ,  YAMADA Kuriko (Hitachi High-Technol. Co., Tokyo, JPN) ,  TAKIMOTO Akio (Shionogi & Co. Ltd., Osaka, JPN) ,  KONDO Hirosato (Shionogi & Co. Ltd., Osaka, JPN) ,  SHIMIZU Hiroki (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Sapporo, JPN) ,  INAZU Toshiyuki (Tokai Univ., Kanagawa, JPN) ,  NAKAHARA Yoshiaki (Tokai Univ., Kanagawa, JPN) ,  NISHIMURA Shin-Ichiro (National Inst. of Advanced Industrial Sci. and Technol. (AIST), Sapporo, JPN) ,  NISHIMURA Shin-Ichiro (Hokkaido Univ., Sapporo, JPN)
Material： Journal of the American Chemical Society  (J Am Chem Soc)
Volume： 127  Issue： 33  Page： 11804-11818  Publication year： Aug. 24, 2005 
JST Material Number： C0254A  ISSN： 0002-7863  CODEN： JACSAT  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *mucoprotein ,...
Semi thesaurus term： carrier ,...

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JST classification (3)： Chemical synthesis  (EB03030J) ,  Carbohydrates and sugar chains in general  (EB06010I) ,  Glycosides  (CF10057O)

Substance index (6)： Fmoc-O-[2-(Acetylamino)-3-O,4-O,6-O-triacetyl-2-deoxy-α-D-galactopyranosyl]-L-Thr-OH ,  N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-[3-O,4-O-diacetyl-6-O-[3-O,4-O,6-O-triacetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]threonine ,  O-[2-(Acetylamino)-3-O-(2-O,3-O,4-O,6-O-tetraacetyl-β-D-galactopyranosyl)-6-O-[2-(acetylamino)-3-O,4-O,6-O-triacetyl-2-deoxy-β-D-glucopyranosyl]-2-deoxy-α-D-galactopyranosyl]-N-(9H-fluorene-9-ylmethoxycarbonyl)serine ,  N-[5-[6-(Acryloylamino)hexyloxyimino]hexanoyl]-Phe-Glu-Ala-His-Gly-Val-O-[6-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Thr-O-[3-O-(β-D-galactopyranosyl)-6-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Ser-Ala-Pro-Asp-O-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Thr-Arg-NH₂ ,  Ala-His-Gly-Val-O-[6-O-[2-(Acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Thr-O-[3-O-(β-D-galactopyranosyl)-6-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Ser-Ala-Pro-Asp-O-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Thr-Arg-NH₂ ,  Ala-His-Gly-Val-O-[6-O-[2-(Acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Thr-O-[3-O-[3-O-(N-acetyl-α-neuraminosyl)-β-D-galactopyranosyl]-6-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Ser-Ala-Pro-Asp-O-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-Thr-Arg-NH₂

Terms in the title (6)： MUC1 ,  糖ペプチド ,  コンビナトリアル合成 ,  ムチン ,  化学 ,  酵素的合成