Art

J-GLOBAL ID：200902260548854940   Reference number：09A0185876

Effect of cell-penetrating peptides on the nasal absorption of insulin

インシュリンの経鼻吸収に及ぼす細胞-貫通性ペプチドの影響

Author (5)： KHAFAGY El-Sayed (Hoshi Univ., Tokyo, JPN) ,  MORISHITA Mariko (Hoshi Univ., Tokyo, JPN) ,  ISOWA Koichi (Center of Japan Biological Chemistry Co. Ltd., Gifu, JPN) ,  IMAI Jun (Center of Japan Biological Chemistry Co. Ltd., Gifu, JPN) ,  TAKAYAMA Kozo (Hoshi Univ., Tokyo, JPN)
Material： Journal of Controlled Release  (J Control Release)
Volume： 133  Issue： 2  Page： 103-108  Publication year： Jan. 19, 2009 
JST Material Number： C0308D  ISSN： 0168-3659  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *bioactive peptide ,...
Semi thesaurus term： insulin ,...

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JST classification (3)： Biological function  (EB03040U) ,  Basic biopharmacy  (GY01021U) ,  Bioactive peptides  (EB08100U)

Substance index (1)： Penetratin

Reference (33)：

• A.E. Pontiroli, A. Calderara, G. Pozza, Intranasal drug delivery. Potential advantages and limitations from a clinical pharmacokinetic perspective, Clin. Pharmacokinet. 17 (1989) 299-307.
• L. Illum, S.S. Davis, Intranasal insulin. Clinical pharmacokinetics, Clin. Pharmacokinet. 23 (1992) 30-41.
• El-S. Khafagy, M. Morishita, Y. Onuki, K. Takayama, Current challenges in non-invasive insulin delivery systems: a comparative review, Adv. Drug Deliv. Rev. 59 (2007) 1521-1546.
• L. Illum, S.S. Davis, Absorption enhancers for nasal drug delivery, Clin. Pharmacokinet. 42 (1992) 1107-1128.
• L. Illum, Nasal drug delivery-possibilities, problems and solutions, J. Control. Release 87 (2003) 187-198.

Terms in the title (4)： インシュリン ,  経鼻吸収 ,  細胞 ,  ペプチド