Art

J-GLOBAL ID：200902260830083026   Reference number：09A0428721

Kujin Suppresses Histamine Signaling at the Transcriptional Level in Toluene 2,4-Diisocyanate-Sensitized Rats

苦参は,トルエン2,4-ジイソシアネート感作ラットにおけるヒスタミンシグナル伝達を転写レベルで抑制する

Author (10)： DEV Shrabanti (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  MIZUGUCHI Hiroyuki (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  DAS Asish K. (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  MAEYAMA Kazutaka (Div. of Pharmacology, Dep. of Integrated Basic Medical Sci., Ehime Univ. School of Medicine, JPN) ,  HORINAGA Shiho (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  KATO Shuhei (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  TAMADA Misaki (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  HATTORI Masashi (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  UMEHARA Hayato (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN) ,  FUKUI Hiroyuki (Dep. of Molecular Pharmacology, Inst. of Health-Biosciences, The Univ. of Tokushima Graduate School, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 109  Issue： 4  Page： 606-617 (J-STAGE)  Publication year： 2009 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *plant preparation ,...
Semi thesaurus term： *Sophorae Radix ,...

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JST classification (2)： Treatment for immunologic diseases,allergic diseases.  (GD04030Y) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (2)： 2,4-Toluene diisocyanate ,  Histamine

Reference (74)：

• KUROYANAGI, M. Anti-bacterial and antiandrogen flavonoids from Sophora flavescens. J Nat Prod. 1999, 62, 1595-1599
• SOHN, HY. Anti-microbial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants : Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis Nakai. Phytomedicine. 2004, 11, 666-672
• KIM, DW. Effects of sophoraflavanone G, a prenylated flavonoid from Sophora flavescens, on cyclooxygenase-2 and in vivo inflammatory response. Arch Pharm Res. 2002, 25, 329-335
• KWON, KB. Sophorae radix extract inhibits high glucose-induced vascular cell adhesion molecule-1 up-regulation on endothelial cell line. Clin Chim Acta. 2004, 348, 79-86
• HOANG, BX. New approach in asthma treatment using excitatory modulator. Phytother Res. 2007, 21, 554-557

Terms in the title (8)： 苦参 ,  トルエン ,  ジイソシアネート ,  感作 ,  ラット ,  ヒスタミン ,  シグナル伝達 ,  転写