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J-GLOBAL ID：200902261082644245   Reference number：07A1216816

Characteristic Properties of Genipin as an Activator in Neuronal Nitric Oxide Synthase

ニューロン酸化窒素シンターゼの活性化剤としてのゲニピンの特徴的性質

Author (7)： SUZUKI Hirokazu (Dep. of Medicinal Chemistry, Fac. of Pharmaceutical Sciences, Hokuriku Univ.) ,  SUZUKI Hirokazu (Organization for Frontier Res. in Preventive Pharmaceutical Sciences, Hokuriku Univ.) ,  YAMAZAKI Matsumi (Dep. of Biochemistry, Fac. of Pharmaceutical Sciences, Hokuriku Univ.) ,  CHIBA Kenzo (Dep. of Biochemistry, Fac. of Pharmaceutical Sciences, Hokuriku Univ.) ,  CHIBA Kenzo (Organization for Frontier Res. in Preventive Pharmaceutical Sciences, Hokuriku Univ.) ,  SAWANISHI Hiroyuki (Dep. of Medicinal Chemistry, Fac. of Pharmaceutical Sciences, Hokuriku Univ.) ,  SAWANISHI Hiroyuki (Organization for Frontier Res. in Preventive Pharmaceutical Sciences, Hokuriku Univ.)
Material： Journal of Health Science  (J Health Sci)
Volume： 53  Issue： 6  Page： 730-733 (J-STAGE)  Publication year： 2007 
JST Material Number： S0030A  ISSN： 1344-9702  CODEN： JHSCFD  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *cofactor ,...
Semi thesaurus term： nitric oxide synthase

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JST classification (1)： Coenzymes  (EB09020O)

Substance index (1)： Genipin

Reference (13)：

• 1) Ishiguro, K., Yamaki, M., Takayi, S., Ikeda, Y., Kawakani, K., Ito, K. and Nose, T. (1983) Studies on iridoid-related compounds, II. The structure and antimicrobial activity of aglycones of galioside and gardenoside. J. Nat. Prod., 46, 532-536.
• 2) Hsu, H. Y., Yang, J. J., Lin, S. Y. and Lin, C. C. (1997) Comparisons of geniposidic acid and geniposide on antitumor and radioprotection after sublethal irradiation. Cancer Lett., 113, 31-37.
• 3) Circosta, C., Occhiuto, F., Ragusa, S., Trovato, A., Tumono, G., Brigurio, F. and De Pasquale, A. (1984) A drug used in traditional medicine: Harpagophytum procumbens DC. II. Cardiovascular activity. J. Ethnopharmacol., 11, 259-274.
• 4) Miyagoshi, M., Amagaya, S. and Ogihara, R. (1988) Choleretic action of iridoid compounds. J. Pharmacobiodyn., 11, 186-190.
• 5) Chang, I. M. (1998) Liver-protective activities of aucubin derived from traditional oriental medicine. Res. Commun. Mol. Pathol. Pharmacol., 102, 189-204.

Terms in the title (5)： ニューロン ,  酸化窒素シンターゼ ,  活性化剤 ,  ゲニピン ,  性質