Art

J-GLOBAL ID：200902261592083426   Reference number：09A0124946

E2F-like elements in p27^Kip1 promoter specifically sense deregulated E2F activity

p27^Kip1プロモータ中のE2F様要素は脱制御E2F活性を特異的に検知する

Author (6)： OZONO Eiko (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  KOMORI Hideyuki (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  IWANAGA Ritsuko (Univ. Colorado Health Sci. Center, CO, USA) ,  IKEDA Masa-Aki (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  ISEKI Sachiko (Tokyo Medical and Dental Univ., Tokyo, JPN) ,  OHTANI Kiyoshi (Tokyo Medical and Dental Univ., Tokyo, JPN)
Material： Genes to Cells  (Genes Cells)
Volume： 14  Issue： 1  Page： 89-99  Publication year： Jan. 2009 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： *transcription factor ,...
Semi thesaurus term： cdk inhibitor ,...

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JST classification (2)： Gene expression  (EC02040Q) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Reference (21)：

• Alevizopoulos, K., Catarin, B., Vlach, J. & Amati, B. (1998) A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27^Kip1. EMBO J. 17, 5987-5997.
• Binne, U.K., Classon, M.K., Dick, F.A., Wei, W., Rape, M., Kaelin, W.G. Jr., Naar, A.M. & Dyson, N.J. (2007) Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit. Nat. Cell Biol. 9, 225-232.
• DeGregori, J. (2002) The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim. Biophys. Acta 1602, 131-150.
• Dimri, G.P., Itahana, K., Acosta, M. & Campisi, J. (2000) Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14ARF tumor suppressor. Mol. Cell. Biol. 20, 273-285.
• Dyson, N. (1998) The regulation of E2F by pRB-family proteins. Genes Dev. 12, 2245-2262.

Terms in the title (5)： p27Kip1 ,  プロモータ ,  E2F ,  要素 ,  活性