Art

J-GLOBAL ID：200902261602111814   Reference number：05A0720472

Effects of Heparin and Its 6-O-and 2-O-Desulfated Derivatives with Low Anticoagulant Activity on Proliferation of Human Neural Stem/Progenitor Cells

ヘパリンとその低抗凝血性活性型6-O-,2-O-脱硫酸化派生体のヒト神経幹/前駆体細胞増殖への影響

Author (9)： MORI Hideki (Res. Inst. for Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol.) ,  KANEMURA Yonehiro (Res. Inst. for Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol.) ,  KANEMURA Yonehiro (Inst. for Clinical Res., Osaka National Hospital, National Hospital Organization) ,  ONAYA Junichi (Central Res. Laboratories, Seikagaku Corp.) ,  HARA Masayuki (Dep. of Applied Bioscience, Inst. for Advanced Sci. and Technol., Osaka Prefecture Univ.) ,  MIYAKE Jun (Res. Inst. for Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol.) ,  YAMASAKI Mami (Inst. for Clinical Res., Osaka National Hospital, National Hospital Organization) ,  YAMASAKI Mami (Dep. of Neurosurgery, Osaka National Hospital, National Hospital Organization) ,  KARIYA Yutaka (Central Res. Laboratories, Seikagaku Corp.)
Material： Journal of Bioscience and Bioengineering  (J Biosci Bioeng)
Volume： 100  Issue： 1  Page： 54-61 (J-STAGE)  Publication year： 2005 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： heparin ,...
Semi thesaurus term： nerve cell ,...

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JST classification (2)： Cell division and proliferation  (EF02020D) ,  Influence on animals  (EE05040R)

Reference (38)：

• 1. Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P., and Ornitz, D. M.: Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell, 64, 841–848 (1991).
• 2. Ishihara, M., Tyrrell, D. J., Stauber, G. B., Brown, S., Cousens, L. S., and Stack, R. J.: Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor. J. Biol. Chem., 268, 4675–4683 (1993).
• 3. Guimond, S., Maccarana, M., Olwin, B. B., Lindahl, U., and Rapraeger, A. C.: Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. J. Biol. Chem., 268, 23906–23914 (1993).
• 4. Ashikari, S., Habuchi, H., and Kimata, K.: Characterization of heparan sulfate oligosaccharides that bind to hepatocyte growth factor. J. Biol. Chem., 270, 29586–29593 (1995).
• 5. Lyon, M., Deakin, J. A., Mizuno, K., Nakamura, T., and Gallagher, J. T.: Interaction of hepatocyte growth factor with heparan sulfate. Elucidation of the major heparan sulfate structural determinants. J. Biol. Chem., 269, 11216–11223 (1994).

Terms in the title (9)： ヘパリン ,  凝血 ,  活性 ,  硫酸化 ,  ヒト ,  神経 ,  幹 ,  前駆体細胞 ,  増殖