Art

J-GLOBAL ID：200902262223445957   Reference number：04A0368838

Targeted gene delivery using humanized single-chain antibody with negatively charged oligopeptide tail

負電荷を持つオリゴヌクレオチド尾部を含むヒト用一本鎖抗体を使った標的遺伝子デリバリー

Author (3)： SUZUKI M (Keio Univ. School of Medicine, Tokyo) ,  TAKAYANAGI A (Keio Univ. School of Medicine, Tokyo) ,  SHIMIZU N (Keio Univ. School of Medicine, Tokyo)
Material： Cancer Science  (Cancer Sci)
Volume： 95  Issue： 5  Page： 424-429  Publication year： May. 10, 2004 
JST Material Number： F0633A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *gene therapy ,...
Semi thesaurus term： A431 cell ,...

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JST classification (1)： Gene manipulation  (EC02050B)

Reference (23)：

• CHEN, J. A novel gene delivery system using EGF receptor-mediated endocytosis. FEBS Lett. 1994, 338, 167-169
• SHIMIZU, N. Use of the growth factor receptor-mediated endocytosis for therapeutic gene delivery : immunogene approach. Cell Pharmacol AIDS Sci. 1996, 3, 263-267
• SHIMIZU, N. Immunogene approach towards cancer therapy using erythrocyte growth factor receptor-mediated gene delivery. Cancer Gene Ther. 1996, 3, 113-120
• CHEN, J. Receptor-mediated gene delivery using the Fab fragments of anti-epidermal growth factor receptor antibodies : improved immunogene approach. Cancer Gene Ther. 1998, 5, 357-364
• CHEN, J. Targeted in vivo delivery of therapeutic gene into experimental squamous cell carcinomas using anti-epidermal growth factor receptor antibody : immunogene approach. Hum Gene Ther. 1998, 9, 2673-2681

Terms in the title (7)： 負電荷 ,  オリゴヌクレオチド ,  尾部 ,  ヒト ,  一本鎖抗体 ,  標的遺伝子 ,  デリバリー