Art

J-GLOBAL ID：200902262627839010   Reference number：04A0635098

Effects of lubricant mixing on compression properties of various kinds of direct compression excipients and physical properties of the tablets

種々の直接圧縮賦形剤の圧縮特性および錠剤の物理的性質に対する潤滑剤混合の影響

Author (3)： OTSUKA M (Kobe Pharmaceutical Univ., Kobe, JPN) ,  YAMANE I (Kobe Pharmaceutical Univ., Kobe, JPN) ,  MATSUDA Y (Kobe Pharmaceutical Univ., Kobe, JPN)
Material： Advanced Powder Technology  (Adv Powder Technol)
Volume： 15  Issue： 4  Page： 477-493  Publication year： 2004 
JST Material Number： W0255A  ISSN： 0921-8831  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： compression ,...
Semi thesaurus term： surface free energy ,...

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JST classification (2)： Production and handling of solid in general  (XD03021O) ,  Solid preparations  (GY02030V)

Reference (23)：

• OTSUKA, M. Effects of mixer and mixing time on the pharmaceutical properties of theophylline tablets containing various kinds of lactose as diluents. Drug. Dev. Ind. Pharm. 1993, 19, 3, 333-348
• SHAH, A. C. Mechanism of surface lubrication : influence of duration of lubricant excipient mixing on processing characteristics of powders and propertyes of compressed tablets. J. Pharm. Sci. 1977, 66, 1377
• KIKUTA, J. Effect of mixing time on the lubricating properties of magnesium stearate and the final characteristics of the compressed tablet. Drug. Dev. Ind. Pharm. 1994, 20, 343-355
• CHOWHAN, Z. T. Drug-excipient interactions resulting from powder mixing 3 : solid state propertyes and their effect on drug dissolution. J. Pharm. Sci. 1986, 75, 534
• CHOWHAN, Z. T. Drug-excipient interactions resulting from powder mixing 5 : role of lubricants and their effect on in vitro dissolution. J. Pharm. Sci. 1986, 75, 542

Terms in the title (5)： 賦形剤 ,  圧縮特性 ,  錠剤 ,  物理的性質 ,  潤滑剤