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J-GLOBAL ID:200902264409714330   Reference number:08A0854441

Dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxin-induced shock in rats

ラットのエンドトキシン誘導ショックに対する死亡率と炎症反応におけるデキスメデトミジンの用量及び時間関連効果
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Volume: 22  Issue:Page: 221-228  Publication year: 2008 
JST Material Number: L0489A  ISSN: 0913-8668  CODEN: JANEEC  Document type: Article
Article type: 原著論文  Country of issue: Germany, Federal Republic of (DEU)  Language: ENGLISH (EN)
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Infectious diseases,parasitics diseases in general.  ,  Basic medicine on cardiovascular system 
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Reference (13):
  • WAKABAYASHI, G. Staphylococcus epidermidis induces complement activation, tumor necrosis factor and interleukin-1, a shock like state and tissue injury in rabbits without endotoxemia ; comparison to Escherichia coli. J Clin Invest. 1991, 87, 1925-1935
  • CASEY, LC. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med. 1993, 119, 771-778
  • MARTY, C. Circulating interleukin-8 concentrations in patients with multiple organ failure of septic and nonseptic origin. Crit Care Med. 1994, 22, 673-679
  • DAMAS, P. Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans. Crit Care Med. 1989, 17, 975-978
  • NATANSON, C. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock. J Exp Med. 1989, 169, 823-832
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