Art
J-GLOBAL ID：200902264676334199   Reference number：08A1180789

Molecular Determinants of hERG Channel Block by Terfenadine and Cisapride

テルフェナジンとシサプリドによるhERGチャンネルブロックの分子決定基
Author (5)：
KAMIYA Kaichiro

About KAMIYA Kaichiro

(Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN)

About Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN

, 
NIWA Ryoko

About NIWA Ryoko

(Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN)

About Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN

, 
MORISHIMA Mikio

About MORISHIMA Mikio

(Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN)

About Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN

, 
HONJO Haruo

About HONJO Haruo

(Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN)

About Dep. of Cardiovascular Res., Res. Inst. of Environmental Medicine, Nagoya Univ., JPN

, 
SANGUINETTI Michael C.

About SANGUINETTI Michael C.

(Dep. of Physiology and Nora Eccles Harrison Cardiovascular Res. & Training Inst., Univ. of Utah, USA)

About Dep. of Physiology and Nora Eccles Harrison Cardiovascular Res. & Training Inst., Univ. of Utah, USA


Material：
Journal of Pharmacological Sciences  (J Pharmacol Sci)

About Journal of Pharmacological Sciences


Volume： 108  Issue： 3  Page： 301-307 (J-STAGE)  Publication year： 2008 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
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histamine H1-receptor blocker

About histamine H1-receptor blocker

,...
Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
HERG

About HERG

,...
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JST classification (1)：
JST classification
Category name(code) classified by JST.
Transport of cell membrane 
(EF04020R)

About Transport of cell membrane

Reference (34)：
  • SANGUINETTI, MC. Two components of cardiac delayed rectifier K^+ current : Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol. 1990, 96, 195-215
  • CURRAN, ME. A molecular basis for cardiac arrhythmia : HERG mutations cause long QT syndrome. Cell. 1995, 80, 795-803
  • KEMP, JP. Antihistamines-is there anything safe to prescribe?. Ann Allergy. 1992, 69, 276-280
  • PRATT, C. Cardiovascular safety of fexofenadine HCl. Clin Exp Allergy. 1999, 29, Suppl 3, 212-215
  • ROY, M-L. HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine. Circ Res. 1996, 94, 817-823
ｍore...
Terms in the title (4)：
Terms in the title
Keywords automatically extracted from the title.
テルフェナジン

About テルフェナジン

, 
シサプリド

About シサプリド

, 
HERGチャンネル

About HERGチャンネル

, 
分子

About 分子


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