Art
J-GLOBAL ID：200902264808219394
Reference number：04A0563521
Existence of Leukemic Clones Resistant to Both Imatinib Mesylate and Rituximab before Drug Therapies in a Patient with Philadelphia Chromosome-Positive Acute Lymphocytic Leukemia
Philadelphia染色体陽性急性リンパ性白血病の1患者における薬物治療前のイマチニブメシラートとリツキシマブの両方に対し耐性を示す白血病クローンの存在
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Material：
Volume：
80
Issue：
1
Page：
62-66
Publication year：
Jul. 15, 2004
JST Material Number：
F0888A
ISSN：
0925-5710
CODEN：
IJHEEY
Document type：
Article
Article type：
原著論文
Country of issue：
Germany, Federal Republic of (DEU)
Language：
ENGLISH (EN)
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JST classification (2)：
JST classification
Category name(code) classified by JST.
Drug therapy(=pharmacotherapy)for tumors
, Blood cell tumors(=neoplasms)
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Reference (30)：
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KANTARJIAN, H. Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med. 2002, 346, 645-652
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HUGHES, TP. Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia. N Engl J Med. 2003, 349, 1423-1432
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DRUKER, BJ. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001, 344, 1038-1042
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OTTMANN, OG. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood. 2002, 100, 1965-1971
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BRANFORD, S. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia of Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. Blood. 2002, 99, 3472-3475
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