Art

J-GLOBAL ID：200902265473352970   Reference number：07A0842681

Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway

新規HER二量化阻害薬ペルツズマブはHER3シグナル伝達経路媒介ヒト肺癌細胞の増殖を抑制する

Author (9)： SAKAI Kazuko (National Cancer Center Hospital, Tokyo) ,  SAKAI Kazuko (Ochanomizu Univ., Tokyo) ,  YOKOTE Hideyuki (National Cancer Center Hospital, Tokyo) ,  YOKOTE Hideyuki (Kinki Univ. School of Medicine, Osaka, JPN) ,  MURAKAMI-MUROFUSHI Kimiko (Ochanomizu Univ., Tokyo) ,  TAMURA Tomohide (National Cancer Center Hospital, Tokyo) ,  SAIJO Nagahiro (National Cancer Center Hospital, Tokyo) ,  NISHIO Kazuto (National Cancer Center Hospital, Tokyo) ,  NISHIO Kazuto (Kinki Univ. School of Medicine, Osaka, JPN)
Material： Cancer Science  (Cancer Sci)
Volume： 98  Issue： 9  Page： 1498-1503  Publication year： Sep. 2007 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： monoclonal antibody ,...
Semi thesaurus term： *ペルツズマブ ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Reference (31)：

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• PARK, OK. In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc Natl Acad Sci USA. 1996, 93, 13704-13708

Terms in the title (7)： 阻害薬 ,  ペルツズマブ ,  HER3 ,  シグナル伝達経路 ,  ヒト ,  肺癌細胞 ,  増殖