Art

J-GLOBAL ID：200902267041253850   Reference number：04A0014785

Synthesis of acyclic nucleotide analogues possessing a difluoromethylene phosphonyl group at the side chain

側鎖にジフルオロメチレンホスホニル基を有する非環式ヌクレオチド類似体の合成

Author (5)： MURANO T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  YUASA Y (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  KOBAYAKAWA H (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  YOKOMATSU T (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN) ,  SHIBUYA S (Tokyo Univ. Pharmacy and Life Sci., Tokyo, JPN)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 59  Issue： 51  Page： 10223-10230  Publication year： Dec. 15, 2003 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *nucleotide analog ,...
Semi thesaurus term： P2Y receptor ,...

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JST classification (1)： Nucleosides,nucleotides  (CF10060K)

Substance index (14)： MRS-2179 ,  2',5'-ADP ,  Adenosine-3',5'-bisphosphoric acid ,  N-Methyl-9-[(3S)-3-(phosphonodifluoromethyl)-5-(phosphonooxy)pentyl]-9H-purine-6-amine ,  N-Methyl-9-[(3R)-3-(phosphonodifluoromethyl)-5-(phosphonooxy)pentyl]-9H-purine-6-amine ,  (2R)-2,3-Isopropylidenedioxypropanal ,  (4S,5S)-4-[(Diethoxythiophophinyl)difluoromethyl]-5-(benzyloxymethyl)tetrahydrofuran-2-one ,  [(2R)-1,1-Difluoro-2-[2-(benzyloxy)ethyl]-4-(triisopropylsilyloxy)butyl]phosphonic acid diethyl ester ,  [(2S)-1,1-Difluoro-2-[2-(benzyloxy)ethyl]-4-hydroxybutyl]phosphonic acid diethyl ester ,  6-Chloro-9H-purine ,  N-Methyl-9-[(3R)-3-[(diethoxyphosphinyl)difluoromethyl]-5-(diethoxyphosphinyloxy)pentyl]-9H-purine-6-amine ,  [(2R)-1,1-Difluoro-2-[2-(triisopropylsilyloxy)ethyl]-4-hydroxybutyl]phosphonic acid diethyl ester ,  Phosphoric acid diethyl[(3S)-3-[(diethoxyphosphinyl)difluoromethyl]-5-hydroxypentyl] ester ,  N-Methyl-9-[(3S)-3-[(diethoxyphosphinyl)difluoromethyl]-5-(diethoxyphosphinyloxy)pentyl]-9H-purine-6-amine

Terms in the title (3)： 側鎖 ,  環 ,  ヌクレオチド類似体